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Spirometric Assessment of Pulmonary Function Tests in Asthma Patients
Mitali B Rathod1, Amal Budensab2, Sarvasv Bhalla3
1Department of General Medicine, NAMO Medical College and Research Centre, Silvassa, IND.
Asthma patients show significantly reduced lung function, with females experiencing a greater decline in key spirometry measures compared to males. This highlights potential differences in asthma severity and progression between genders.
Area of Science:
- Pulmonary Medicine
- Respiratory Physiology
- Clinical Research
Background:
- Asthma is a chronic inflammatory airway disease causing significant morbidity and mortality.
- Spirometry is crucial for objectively measuring airflow obstruction in asthma patients.
Purpose of the Study:
- To assess pulmonary function test parameters in asthma patients.
- To compare observed spirometry values with predicted values.
- To conduct a gender-wise comparison of spirometry indices.
Main Methods:
- A cross-sectional study involving 120 asthma patients at a tertiary care center.
- Spirometry was performed to record forced vital capacity (FVC), forced expiratory volume in one second (FEV1), FEV1/FVC ratio, peak expiratory flow rate (PEFR), and maximal voluntary ventilation (MVV).
Main Results:
- Asthma patients exhibited significantly lower observed values for FVC, FEV1, FEV1/FVC ratio, PEFR, and MVV compared to predicted values (p < 0.05 for all).
- Female asthma patients showed a significant decline in FVC, FEV1, FEV1/FVC ratio, and MVV compared to males (p < 0.05 for all).
Conclusions:
- Asthma patients demonstrate impaired lung function upon initial assessment.
- Female asthma patients may be at a higher risk for asthma severity compared to males.
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