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Extraskeletal Ewing Sarcoma: A Case Report
Ryan Denis1, Martin Felix1, Daniela Mejia1
1Internal Medicine, St. George's University School of Medicine, St. George, GRD.
Cureus
|March 29, 2024
Summary
This report details a rare extraskeletal Ewing sarcoma in an adult woman, highlighting an unusual presentation of this bone cancer. The findings contribute to understanding this rare malignancy for improved patient care.
Area of Science:
- Oncology
- Genetics
Background:
- Ewing sarcoma typically affects younger individuals and originates in bone.
- Extraskeletal Ewing sarcoma (EES) is rare and can occur outside the typical age range.
Observation:
- A 42-year-old woman presented with a subcutaneous soft tissue mass in her posterior chest.
- Diagnostic tests confirmed a positive EWSR1 gene rearrangement via fluorescence in situ hybridization.
Findings:
- The patient was diagnosed with extraskeletal Ewing sarcoma, a rare variant.
- Chemotherapy demonstrated a favorable response in reducing tumor size, despite complications.
Implications:
- This case expands the understanding of EES presentation and clinical behavior.
- Further research into EES in non-typical demographics and locations is warranted.
- Improved diagnostic and therapeutic strategies for EES may arise from studying rare cases.
