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Perioperative Delta Weight and Pediatric Obstructive Sleep Apnea Resolution after Adenotonsillectomy
Quynh-Chi L Dang1, Seckin Ulualp1, Ron B Mitchell1
1Department of Otolaryngology, Head and Neck Surgery, Southwestern Medical Center at Dallas, University of Texas, Dallas, Texas, U.S.A.
Insights
Weight gain after adenotonsillectomy for pediatric obstructive sleep apnea (OSA) is linked to poorer treatment outcomes. Counseling on weight management before surgery is recommended for children with OSA.
Area of Science:
- Pediatric Otolaryngology
- Sleep Medicine
- Obstructive Sleep Apnea Research
Background:
- Adenotonsillectomy is the primary treatment for pediatric obstructive sleep apnea (OSA).
- Post-operative weight gain following this procedure is a recognized clinical observation.
Purpose of the Study:
- To investigate the correlation between peri-adenotonsillectomy weight changes and the resolution rates of pediatric OSA.
- To determine if increased weight gain around the time of surgery impacts treatment success.
Main Methods:
- Retrospective cohort study of 250 pediatric patients (ages 2-17).
- Analysis of polysomnography data and body mass index (BMI) changes from electronic health records.
- Statistical analysis including univariate and multivariate logistic regression.
Main Results:
- Weight gain around adenotonsillectomy significantly predicts residual OSA.
- Each 1-kg weight increase elevates the odds of residual OSA (AHI >5) by 6.0% and severe OSA (AHI >10) by 8%.
- Higher pre-operative apnea-hypopnea index (AHI), Black/African American race, and male sex were also associated with incomplete OSA resolution.
Conclusions:
- Increased peri-adenotonsillectomy weight gain is associated with higher rates of residual pediatric OSA.
- Pre-operative counseling on weight management strategies is crucial for patients and families undergoing adenotonsillectomy.
Objective(S):
The first-line treatment for pediatric obstructive sleep apnea (OSA) is adenotonsillectomy. Post-operative weight gain is a well-documented phenomenon. We hypothesized that higher peri-adenotonsillectomy delta weight correlates with lower rates of OSA resolution in pediatric patients.
Methods:
This was a retrospective cohort study consisting of 250 patients from 2 to 17 years of age at a tertiary academic medical center between January 2021 and December 2022. Polysomnography results and body mass index (BMI) changes were collected through the electronic health record. Univariate and multivariate logistical regression analyses were performed, adjusting for confounding factors.
Results:
Perioperative delta weight and pre-operative baseline AHI values were significant predictors of residual OSA. For every 1-kilogram gain in weight, the odds of residual OSA (AHI >5) increase by 6.0% (OR = 1.06, 95% CI = 1.02-1.10, p < 0.002), and the odds of residual severe OSA (AHI > 10) increase by 8% (OR = 1.08, 95% CI = 1.04-1.12, p < 0.001). Increased AHI, Black/African American race, and male sex were also factors associated with incomplete OSA resolution.
Conclusions:
Increased peri-adenotonsillectomy delta weight is associated with higher rates of residual OSA in children. Patients and families should be counseled about appropriate weight loss and control methods before adenotonsillectomy.
Level Of Evidence:
IV Laryngoscope, 134:4141-4147, 2024.
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