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Glucocorticoid prescribing in neurology.
Andrew P Jones1, Miguel Debono2, Jennifer Walsh3
1Neurology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Practical Neurology
|March 29, 2024
Summary
Glucocorticoids are vital for neurological disorders but carry risks like adrenal insufficiency. This guide offers strategies, including monitoring and checklists, to mitigate corticosteroid side effects for safer patient care.
Area of Science:
- Pharmacology
- Neurology
- Endocrinology
Background:
- Glucocorticoids are frequently prescribed for various neurological conditions.
- Their use is associated with significant adverse effects, impacting multiple organ systems.
Purpose of the Study:
- To highlight the potential risks associated with corticosteroid prescribing in neurological disorders.
- To provide up-to-date, multispecialty guidance for mitigating these risks.
- To promote safer corticosteroid prescribing practices.
Main Methods:
- Review of current literature and clinical guidelines on corticosteroid use.
- Integration of multispecialty expert input.
- Discussion of risk mitigation strategies, including monitoring and checklists.
Main Results:
- Identification of key adverse effects: adrenal insufficiency, hyperglycemia, osteoporosis, infection risk.
- Emphasis on the necessity of proactive risk management for long-term corticosteroid users.
- Introduction of practical tools like home blood glucose monitoring and a steroid safety checklist.
Conclusions:
- Adherence to updated guidance and implementation of safety measures are crucial for minimizing corticosteroid-related harm.
- Multispecialty collaboration enhances the development of effective risk mitigation strategies.
- Proactive monitoring and the use of safety checklists can significantly improve patient outcomes in neurological disorders treated with corticosteroids.
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