CSCA U-Net: A channel and space compound attention CNN for medical image segmentation

Image segmentation is one of the vital steps in medical image analysis. A large number of methods based on convolutional neural networks have emerged, which can extract abstract features from multiple-modality medical images, learn valuable information that is difficult to recognize by humans, and obtain more reliable results than traditional image segmentation approaches. U-Net, due to its simple structure and excellent performance, is widely used in medical image segmentation. In this paper, to further improve the performance of U-Net, we propose a channel and space compound attention (CSCA) convolutional neural network, CSCA U-Net in abbreviation, which increases the network depth and employs a double squeeze-and-excitation (DSE) block in the bottleneck layer to enhance feature extraction and obtain more high-level semantic features. Moreover, the characteristics of the proposed method are three-fold: (1) channel and space compound attention (CSCA) block, (2) cross-layer feature fusion (CLFF), and (3) deep supervision (DS). Extensive experiments on several available medical image datasets, including Kvasir-SEG, CVC-ClinicDB, CVC-ColonDB, ETIS, CVC-T, 2018 Data Science Bowl (2018 DSB), ISIC 2018, and JSUAH-Cerebellum, show that CSCA U-Net achieves competitive results and significantly improves generalization performance. The codes and trained models are available at https://github.com/xiaolanshu/CSCA-U-Net.