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HR-BGCN : Predicting readmission for heart failure from electronic health records
Huiting Ma1, Dengao Li1, Jumin Zhao2
1College of Computer Science and Technology (College of Data Science), Taiyuan University of Technology, Taiyuan, 030024, China; Key Laboratory of Big Data Fusion Analysis and Application of Shanxi Province, Taiyuan, 030024, China; Intelligent Perception Engineering Technology Center of Shanxi, Taiyuan, 030024, China.
Insights
This study introduces the HR-BGCN model to predict heart failure readmissions. The model significantly improves prediction accuracy, aiming to reduce patient readmission rates and healthcare costs.
Area of Science:
- Medical Informatics
- Artificial Intelligence in Healthcare
- Clinical Decision Support Systems
Background:
- Heart failure poses a significant public health challenge, characterized by high costs and mortality, exacerbated by difficulties in predicting patient readmissions.
- Accurate readmission prediction models are crucial for clinical decision-making, patient management, and mitigating the economic burden of heart failure.
Purpose of the Study:
- To develop and evaluate a novel model, HR-BGCN, for predicting patient readmission after heart failure hospitalization.
- To enhance the accuracy of readmission prediction by addressing data imbalance and improving feature representation.
Main Methods:
- Utilized patient discharge records from the MIMIC-III database, categorizing patients into no readmission, within 30 days, and after 30 days groups.
- Proposed the HR-BGCN model incorporating Adaptive-TMix for handling category imbalance and a knowledge-informed graph attention mechanism to enhance node feature representation.
- Integrated paragraph-level graph learning representations with BERT's token-level representations for a multi-classification task.
Main Results:
- The HR-BGCN model achieved an average F1 score of 88.26% and an average accuracy of 90.47% for predicting 30-day heart failure readmissions.
- Demonstrated superior performance compared to established graph learning models like IA-GCN and GAT in predicting heart failure readmissions.
Conclusions:
- The HR-BGCN model offers a significant advancement in predicting 30-day heart failure readmissions.
- This model can serve as a valuable tool for clinicians to proactively identify at-risk patients, thereby reducing readmission rates and improving patient outcomes.
Abstract:
Heart failure has become a huge public health problem, and failure to accurately predict readmission will further lead to the disease's high cost and high mortality. The construction of readmission prediction model can assist doctors in making decisions to prevent patients from deteriorating and reduce the cost burden. This paper extracts the patient discharge records from the MIMIC-III database. It divides the patients into three research categories: no readmission, readmission within 30 days, and readmission after 30 days, to predict the readmission of patients. We propose the HR-BGCN model to predict the readmission of patients. First, we use the Adaptive-TMix to improve the prediction indicators of a few categories and reduce the impact of unbalanced categories. Then, the knowledge-informed graph attention mechanism is proposed. By introducing a document-level explicit diagram structure, the coding ability of graph node features is significantly improved. The paragraph-level representation obtained through graph learning is combined with the context token-level representation of BERT, and finally, the multi-classification task is carried out. We also compare several typical graph learning classification models to verify the model's effectiveness, such as the IA-GCN model, GAT model, etc. The results show that the average F1 score of the HR-BGCN model proposed in this paper for 30-day readmission of heart failure patients is 88.26%, and the average accuracy is 90.47%. The HR-BGCN model is significantly better than the graph learning classification model for predicting heart failure readmission. It can help doctors predict the 30-day readmission of patients, then reduce the readmission rate of patients.
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