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Endoscopic duodenal mucosa ablation: the future of diabetes treatment?
Giovanni Musso1, Maurizio Cassader2, Roberto Gambino2
1MECAU, San Luigi Gonzaga Hospital, University of Turin, Turin, Italy.
Trends in Molecular Medicine
|March 29, 2024
Abstract:
Duodenal mucosa ablation (DMA) is a novel approach to treat diabetes, consisting of endoscopic ablation of dysfunctional diabetic duodenal mucosa, which, following the healing response, is replaced by normally functioning mucosa. Two techniques, duodenal mucosal resurfacing (DMR) and recellularization via electroporation therapy (ReCET), recently showed promise in type 2 diabetes mellitus (T2DM) patients.

