Swallowing in advanced oral cancers: A prospective observational study

  • 0Department of Head and Neck Surgical Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India.

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Summary

This summary is machine-generated.

Advanced oral cancer treatments significantly impair swallowing function long after therapy concludes. Early intervention and rehabilitation are crucial for managing this persistent dysphagia in cancer survivors.

Area Of Science

  • Oncology
  • Otolaryngology
  • Speech-Language Pathology

Background

  • Advanced head and neck cancers frequently cause swallowing dysfunction due to anatomical and treatment-related changes.
  • Limited research exists on swallowing function following surgery and multi-modality therapy for advanced oral cancers.
  • This study addresses the gap by longitudinally assessing swallowing dysfunction in locally advanced oral cancers.

Purpose Of The Study

  • To longitudinally assess and compare pre- and post-therapy swallowing dysfunction.
  • To evaluate the impact of surgery and adjuvant therapy on swallowing function in advanced oral cancer patients.

Main Methods

  • Prospective observational longitudinal study at a tertiary cancer center (2017-2018).
  • Included treatment-naive cT4a oral cancer patients (AJCC 7th edition).
  • Swallowing function assessed pre-surgery, post-surgery, and post-adjuvant therapy using Dysphagia score, Penetration-Aspiration Scale (PAS), and Yale pharyngeal residue scales.

Main Results

  • Postoperatively, 47.4%-52.6% of patients showed deterioration in swallowing function scores (Dysphagia, PAS, residue).
  • Six months post-adjuvant therapy, 47.4%-68.4% of patients still exhibited impaired swallowing function.
  • Dysphagia scores demonstrated good correlation with other objective swallowing assessment measures.

Conclusions

  • Surgery and adjuvant therapy significantly impact swallowing function, with deficits persisting for at least six months post-treatment.
  • Early and appropriate rehabilitation interventions are essential to mitigate long-term swallowing problems.
  • Dysphagia scores serve as a reliable predictor of swallowing status, comparable to objective assessments.