Swallowing in advanced oral cancers: A prospective observational study
- Akshat Malik 1, Florida Sharin 1, Arun Balaji 2, Yash Mathur 1, Sudhir Nair 1, Pankaj Chaturvedi 1, Deepa Nair 1
- Akshat Malik 1, Florida Sharin 1, Arun Balaji 2
- 1Department of Head and Neck Surgical Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India.
- 2Department of Speech and Language Pathology, Tata Memorial Centre, Mumbai, Maharashtra, India.
- 0Department of Head and Neck Surgical Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India.
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View abstract on PubMed
Summary
This summary is machine-generated.Advanced oral cancer treatments significantly impair swallowing function long after therapy concludes. Early intervention and rehabilitation are crucial for managing this persistent dysphagia in cancer survivors.
Area Of Science
- Oncology
- Otolaryngology
- Speech-Language Pathology
Background
- Advanced head and neck cancers frequently cause swallowing dysfunction due to anatomical and treatment-related changes.
- Limited research exists on swallowing function following surgery and multi-modality therapy for advanced oral cancers.
- This study addresses the gap by longitudinally assessing swallowing dysfunction in locally advanced oral cancers.
Purpose Of The Study
- To longitudinally assess and compare pre- and post-therapy swallowing dysfunction.
- To evaluate the impact of surgery and adjuvant therapy on swallowing function in advanced oral cancer patients.
Main Methods
- Prospective observational longitudinal study at a tertiary cancer center (2017-2018).
- Included treatment-naive cT4a oral cancer patients (AJCC 7th edition).
- Swallowing function assessed pre-surgery, post-surgery, and post-adjuvant therapy using Dysphagia score, Penetration-Aspiration Scale (PAS), and Yale pharyngeal residue scales.
Main Results
- Postoperatively, 47.4%-52.6% of patients showed deterioration in swallowing function scores (Dysphagia, PAS, residue).
- Six months post-adjuvant therapy, 47.4%-68.4% of patients still exhibited impaired swallowing function.
- Dysphagia scores demonstrated good correlation with other objective swallowing assessment measures.
Conclusions
- Surgery and adjuvant therapy significantly impact swallowing function, with deficits persisting for at least six months post-treatment.
- Early and appropriate rehabilitation interventions are essential to mitigate long-term swallowing problems.
- Dysphagia scores serve as a reliable predictor of swallowing status, comparable to objective assessments.
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