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Extensive Hepatic Infarction due to Polycythemia Vera
Kazuhiro Furukawa1, Fumihiro Urano2, Shozo Okamura3
1Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan. kazufuru@med.nagoya-u.ac.jp.
Polycythemia vera, a JAK2-mutated cancer, can cause rare splanchnic vein thrombosis. This case highlights successful conservative management of hepatic infarction in a polycythemia vera patient.
Area of Science:
- Hematology
- Oncology
- Vascular Medicine
Background:
- Polycythemia vera (PV) is a BCR-ABL1-negative myeloproliferative neoplasm.
- It is characterized by JAK2 mutations, leading to erythrocytosis.
- PV increases the risk of thromboembolic events and disease progression.
Observation:
- Splanchnic vein thrombosis is a rare but serious complication of PV.
- Hepatic infarction is an uncommon manifestation of splanchnic vein thrombosis.
- This report details a specific case of hepatic infarction in a PV patient.
Findings:
- The patient presented with hepatic infarction secondary to polycythemia vera.
- Conservative treatment strategies were employed for management.
- The hepatic infarction was successfully managed without surgical intervention.
Implications:
- Conservative management can be effective for hepatic infarction in PV patients.
- This approach may offer an alternative to more invasive procedures.
- Further research into optimal treatment strategies for PV-related splanchnic vein thrombosis is warranted.
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