Recurrent Takotsubo Syndrome: How Frequent, and How Does It Present?
Jen-Li Looi1, Aleisha Easton1, Mark Webster2
1Department of Cardiology, Middlemore Hospital, Otahuhu, Auckland, New Zealand.
Heart, Lung & Circulation
|March 30, 2024
Summary
Approximately 1 in 10 Takotsubo syndrome patients experience recurrence, often years later. The triggers and echocardiographic patterns may differ in recurrent cases.
Area of Science:
- Cardiology
- Internal Medicine
- Clinical Research
Background:
- Recurrent Takotsubo syndrome (TS) is infrequently studied due to limited data and follow-up.
- Understanding the characteristics and outcomes of recurrent TS is crucial for patient management.
Purpose of the Study:
- To describe the clinical features and outcomes of patients with recurrent Takotsubo syndrome.
- To analyze the characteristics of recurrent TS in a large Auckland cohort.
Main Methods:
- Prospective assessment of clinical profile, in-hospital, and long-term outcomes.
- Study included consecutive patients with recurrent TS from January 2006 to January 2023.
Main Results:
- 9.6% of discharged Takotsubo syndrome patients experienced recurrence (45 out of 467).
- Recurrence occurred a median of 3.14 years after the initial event, with varied stressors and echocardiographic variants.
- All recurrent TS patients were discharged alive; late deaths were predominantly non-cardiac.
Conclusions:
- Recurrent Takotsubo syndrome affects approximately 1 in 10 patients.
- Recurrent events can manifest years after the initial episode.
- Triggers and echocardiographic patterns may differ in recurrent Takotsubo syndrome.
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