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Updated: Jun 29, 2025

Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
Double lung transplantation is better than single lung transplantation for end-stage chronic obstructive pulmonary
Yu-Chi Fang1, Wen-Hsin Cheng1, Hung-I Lu1
1Department of Thoracic & Cardiovascular Surgery, Kaohsiung Chang Gung Memorial Hospital, No. 123 Dapi Road, Niaosong Dist., Kaohsiung, Taiwan, ROC.
Background:
Lung transplantation is one of the most common treatment options for patients with end-stage chronic obstructive pulmonary disease. However, the choice between single and double lung transplantation for these patients remains a matter of debate. Therefore, we performed a systematic search of medical databases for studies on single lung transplantation, double lung transplantation, and chronic obstructive pulmonary disease.
Methods:
The rate ratio and hazard ratio of survival were analyzed. The meta-analysis included 15 case-control and retrospective registry studies.
Results:
The rate ratios of the 3-year survival (0.937 and P = 0.041) and 5-year survival (0.775 and P = 0.000) were lower for single lung transplantation than for double lung transplantation. However, the hazard ratio did not differ significantly between the two.
Conclusions:
Double lung transplantation was found to provide better benefits than single lung transplantation in terms of the long-term survival in patients with chronic obstructive pulmonary disease.
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