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Updated: Jun 29, 2025

Screening Assays to Characterize Novel Endothelial Regulators Involved in the Inflammatory Response
Published on: September 15, 2017
Engagement with nature and proinflammatory biology
Anthony D Ong1, Dakota W Cintron2, Gabriel L Fuligni3
1Department of Psychology, Cornell University, New York; Center for Integrative Developmental Science, Cornell University, New York; Division of Geriatrics and Palliative Medicine, Weill Cornell Medical College, New York.
Background:
Prior evidence indicates that contact with nature improves physical health, but data explicitly linking engagement with nature to biological processes are limited.
Design:
Leveraging survey and biomarker data from 1,244 adults (mean age = 54.50 years, range = 34-84 years) from the Midlife in the United States (MIDUS II) study, we examined associations between nature engagement, operationalized as the frequency of pleasant nature encounters, and systemic inflammation. Concentrations of interleukin-6 (IL-6), C-reactive protein (CRP), and fibrinogen were measured from fasting blood samples. Analyses adjusted for sociodemographic, health behavior, and psychological well-being covariates.
Results:
More frequent positive nature contact was independently associated with lower circulating levels of inflammation.
Conclusions:
These findings add to a growing literature on the salubrious health effects of nature by demonstrating how such experiences are instantiated in downstream physiological systems, potentially informing future interventions and public health policies.
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