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New perspectives on tracheal resection for COVID-19-related stenosis: A propensity score matching analysis

  • 0Division of Thoracic Surgery, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.
The Journal of Thoracic and Cardiovascular Surgery +

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March 31, 2024

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March 31, 2024

View abstract on PubMed

Summary

This summary is machine-generated.

Tracheal resection is safe for COVID-19 survivors with tracheal stenosis. However, post-COVID-19 patients experienced higher rates of intensive care unit admission and complications like reintubation and dysphonia compared to non-COVID-19 patients.

Area Of Science

  • Medicine
  • Surgery
  • Pulmonology

Background

  • Prolonged invasive mechanical ventilation in COVID-19 patients may lead to increased tracheal stenosis.
  • Tracheal stenosis postintubation/tracheostomy requires surgical intervention.

Purpose Of The Study

  • To compare postoperative outcomes of tracheal resection in post-COVID-19 patients versus non-COVID-19 patients.
  • To evaluate the safety and efficacy of tracheal resection for COVID-19-related tracheal stenosis.

Main Methods

  • Single-center, retrospective study of 147 tracheal resections (24 post-COVID-19, 123 non-COVID-19).
  • 1:1 propensity score matching created two groups of 24 patients each.
  • Analysis focused on postoperative outcomes and complications.

Main Results

  • No surgical mortality was observed.
  • Post-COVID-19 patients had higher rates of posttracheostomy stenosis (20 vs 11), ICU admissions (16 vs 9), reintubations (7 vs 2), and dysphonia (46% vs 16%).
  • All differences were statistically significant (P < .05).

Conclusions

  • Tracheal resection is a safe and effective treatment for COVID-19-related tracheal stenosis.
  • Post-COVID-19 patients face increased postoperative complications and ICU admissions after tracheal resection compared to non-COVID-19 patients.

Keywords: