Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

5.1K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
5.1K
Mutual Inductance01:24

Mutual Inductance

2.3K
Inductance is the property of a device that tells us how effectively it induces an emf in another device. In other words, it is a physical quantity that expresses the effectiveness of a given device.
When two circuits carrying time-varying currents are close to one another, the magnetic flux through each circuit varies because of the changing current in the other circuit. Consequently, an emf is induced in each circuit by the changing current in the other. Therefore, this type of emf is called...
2.3K
Atomic Nuclei: Magnetic Resonance01:05

Atomic Nuclei: Magnetic Resonance

650
The number of nuclear spins aligned in the lower energy state is slightly greater than those in the higher energy state. In the presence of an external magnetic field, as the spins precess at the Larmor frequency, the excess population results in a net magnetization oriented along the z axis. When a pulse or a short burst of radio waves at the Larmor frequency is applied along the x axis, the coupling of frequencies causes resonance and flips the nuclear spins of the excess population from the...
650
Double Resonance Techniques: Overview01:12

Double Resonance Techniques: Overview

201
Double resonance techniques in Nuclear Magnetic Resonance (NMR) spectroscopy involve the simultaneous application of two different frequencies or radiofrequency pulses to manipulate and observe two distinct nuclear spins. One important application of double resonance is spin decoupling, which selectively suppresses coupling with one type of nucleus while observing the NMR signal from another nucleus, simplifying the spectrum and enhancing resolution.
Spin decoupling is usually achieved by...
201
Induction01:16

Induction

4.0K
An emf is induced when the magnetic field in a coil is changed by pushing a bar magnet into or out of the coil. emfs of opposite signs are produced by motion in opposite directions, and the directions of emfs are also reversed by reversing poles. The same results are produced if the coil is moved rather than the magnet—it is the relative motion that is important. The faster the motion, the greater the emf. Additionally, there is no emf when the magnet is stationary relative to the coil.
A...
4.0K
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)01:15

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)

310
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...
310

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Continuous Coagulation Monitoring in Human Blood Samples via Magnetic Particle Spectroscopy.

International journal of nanomedicine·2026
Same author

Simple-to-Fabricate and Water-Stable Instrument Markers for Preclinical Magnetic Particle Imaging and Magnetic Resonance Imaging.

Medical devices (Auckland, N.Z.)·2026
Same author

Multi-contrast magnetic particle imaging for tomographic pH monitoring using stimuli-responsive hydrogels.

Communications engineering·2026
Same author

NMR relaxometry probes solvent-polarity-dependent molecular interactions in stimuli-responsive lyogels.

Physical chemistry chemical physics : PCCP·2025
Same author

Superferromagnetic Disk Particles for Magnetic Particle Imaging.

Small methods·2025
Same author

Approaching the physical limits of specific absorption rate for synthetic antiferromagnetic nanodisks in hyperthermia applications.

Biomaterials science·2025

Related Experiment Video

Updated: Jun 29, 2025

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
07:01

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

9.6K

Resonant inductive coupling network for human-sized magnetic particle imaging.

Fabian Mohn1,2, Fynn Förger1,2, Florian Thieben1,2

  • 1Institute for Biomedical Imaging, Hamburg University of Technology, 21073 Hamburg, Germany.

The Review of Scientific Instruments
|April 1, 2024
PubMed
Summary

This study introduces a novel inductive coupling network for magnetic particle imaging (MPI) systems, enhancing patient safety and signal quality. The new design optimizes the drive field generator for improved performance in human-sized scanners.

More Related Videos

Optimized Setup and Protocol for Magnetic Domain Imaging with In Situ Hysteresis Measurement
09:43

Optimized Setup and Protocol for Magnetic Domain Imaging with In Situ Hysteresis Measurement

Published on: November 7, 2017

9.5K
Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics
07:42

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics

Published on: February 19, 2017

8.8K

Related Experiment Videos

Last Updated: Jun 29, 2025

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples
07:01

Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

Published on: June 9, 2016

9.6K
Optimized Setup and Protocol for Magnetic Domain Imaging with In Situ Hysteresis Measurement
09:43

Optimized Setup and Protocol for Magnetic Domain Imaging with In Situ Hysteresis Measurement

Published on: November 7, 2017

9.5K
Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics
07:42

Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics

Published on: February 19, 2017

8.8K

Area of Science:

  • Biomedical Engineering
  • Medical Imaging Physics
  • Electrical Engineering

Background:

  • Magnetic Particle Imaging (MPI) requires precise control of magnetic fields for imaging.
  • Human-sized MPI systems necessitate high-current drive field generators operating in the kHz range.
  • Effective matching and tuning are crucial for power amplifiers, filters, and drive field generators.

Purpose of the Study:

  • To develop a safe and efficient inductive coupling network for human-sized MPI scanners.
  • To achieve floating potentials for patient safety and high linearity/gain for the resonant transformer.
  • To optimize the design of the drive field generator for improved MPI performance.

Main Methods:

  • A symmetrical topology and transformer-based inductive coupling network were employed.
  • A novel systematic approach was used to design a loss-optimized resonant toroid with a D-shaped cross-section.
  • Segmentation was utilized to adjust the inductance-to-resistance ratio while maintaining a constant quality factor.
  • A specific matching condition for a symmetric transmit-receive circuit was derived.
  • Decoupling of multiple drive field channels and optimization of the transformer's primary side were investigated.

Main Results:

  • Two prototypes of the inductive coupling network were constructed and measured.
  • The experimental results were compared to derived theory and simulations.
  • The design achieved floating potentials for enhanced patient safety.
  • High linearity and gain for the resonant transformer were attained.
  • The system demonstrated effective filtering of the fundamental frequency for simultaneous signal transmission and reception.

Conclusions:

  • The developed inductive coupling network is effective for human-sized MPI systems.
  • The novel design approach ensures patient safety and improves signal transmission and reception.
  • The findings contribute to the advancement of safer and more efficient MPI technology.