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Related Experiment Video

Updated: Jun 29, 2025

Segmentation and Linear Measurement for Body Composition Analysis using Slice-O-Matic and Horos
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A body shape index (ABSI) but not body mass index (BMI) is associated with prostate cancer-specific mortality:

Hui-Chen Ku1, Evelyn Cheng2, Ching-Feng Cheng1,3,4

  • 1Department of Pediatrics, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.

The Prostate
|April 1, 2024
PubMed
Summary
This summary is machine-generated.

High abdominal obesity, measured by the abdominal to height ratio (ABSI), is linked to increased prostate cancer mortality in men diagnosed within four years. Body mass index (BMI) showed no significant association with mortality risk.

Keywords:
National Health and Nutrition Examination Survey (NHANES)a body shape indexbody mass index (BMI)mortalityprostate cancer

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Area of Science:

  • Oncology
  • Epidemiology
  • Obesity Research

Background:

  • Obesity is a potential factor in prostate cancer (PCa) development and progression.
  • The association between visceral obesity, assessed by the abdominal to height ratio (ABSI), and PCa mortality requires further investigation.
  • This study examines the relationship between ABSI, body mass index (BMI), and long-term PCa-specific mortality.

Purpose of the Study:

  • To assess the association between ABSI and BMI with PCa-specific mortality.
  • To investigate the role of visceral obesity in PCa outcomes.
  • To analyze long-term mortality data in a US population.

Main Methods:

  • A population-based longitudinal study using the National Health and Nutrition Examination Survey (2001-2010) database.
  • Inclusion criteria: males aged ≥40 years diagnosed with PCa, who underwent surgery and/or radiation.
  • Statistical analyses included Cox proportional hazards regression and ROC curve analysis, with follow-up through 2019.

Main Results:

  • No significant association was found between BMI or continuous ABSI and PCa-specific mortality in the overall cohort.
  • However, among men diagnosed within 4 years, the highest ABSI quartile was significantly associated with increased PCa-specific mortality (aHR=5.34, p=0.001).
  • BMI did not show a significant association in this subgroup. ROC analysis indicated ABSI's predictive value for mortality in this specific group.

Conclusions:

  • High ABSI, but not BMI, is independently associated with increased PCa-specific mortality in US males diagnosed with PCa within the last four years.
  • Visceral obesity, as indicated by ABSI, may be a significant predictor of mortality in early-stage PCa patients.
  • Further research is warranted to explore the clinical implications of ABSI in PCa management.