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Sodium valproate in tardive dyskinesia
The Journal of Clinical Psychiatry
|November 1, 1979
Summary
Sodium valproate, a GABA-ergic agent, showed moderate improvement in tardive dyskinesia symptoms. Further research into GABA-ergic compounds for tardive dyskinesia treatment is warranted.
Area of Science:
- Neuroscience
- Pharmacology
Background:
- Tardive dyskinesia (TD) is a movement disorder often associated with dopaminergic and cholinergic system imbalances.
- Emerging evidence suggests a role for GABA-ergic (gamma-aminobutyric acid) pathways in TD pathophysiology.