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Patients' Preference for Pharmaceutical Dosage Forms: Does It Affect Medication Adherence? A Cross-Sectional Study in
Liknaw Workie Limenh1, Tewodros Ayalew Tessema1, Wudneh Simegn2
1Department of Pharmaceutics, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Patient preference for medication dosage forms, like tablets and oral administration, impacts drug adherence. Factors such as gender, location, and medication cost significantly influence medication discontinuation.
Area of Science:
- Pharmaceutical Sciences
- Public Health
- Patient Adherence Research
Background:
- Dosage forms (DF) are critical factors influencing patient adherence to medication.
- Patient preferences for pharmaceutical DF can significantly impact medication adherence.
- Understanding these preferences is key to improving therapeutic outcomes.
Purpose of the Study:
- To evaluate how patient preferences for pharmaceutical dosage forms affect medication adherence.
- To identify factors influencing medication discontinuation in community pharmacies.
- To provide insights for enhancing patient adherence and therapeutic outcomes.
Main Methods:
- A cross-sectional study was conducted in community pharmacies in Gondar town.
- Data were collected from June 25 to July 27, 2023.
- Bivariate and multivariate logistic regressions were used to analyze factors associated with medication discontinuation.
Main Results:
- Tablets were the most preferred dosage form (42.4%), with small-sized medications being most desirable.
- The oral route of administration was highly preferred (71.2%).
- Significant factors associated with medication discontinuation included being male, rural residence, DF type, high administration frequency, high cost, perceived improvement, and number of drugs.
Conclusions:
- Tablet dosage forms, oral administration, and once-daily regimens were most preferred.
- Several demographic, medication-related, and treatment-related factors were significantly associated with medication discontinuation.
- Considering patient preferences and identified risk factors is crucial for improving medication adherence and treatment success.
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