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Formulating biopharmaceuticals using three-dimensional printing.

Alistair K C Chan1,2, Nehil Ranjitham Gopalakrishnan1,2, Yannick Leandre Traore1,2

  • 1School of Pharmacy, University of Waterloo, Kitchener, ON, Canada.

Journal of Pharmacy & Pharmaceutical Sciences : a Publication of the Canadian Society for Pharmaceutical Sciences, Societe Canadienne Des Sciences Pharmaceutiques
|April 1, 2024
PubMed
Summary
This summary is machine-generated.

Three-dimensional (3D) printing is revolutionizing medicine and drug delivery, moving beyond the "one size fits all" approach. This technology enables personalized medicine through advanced, modified drug delivery systems.

Keywords:
additive manufacturingdrug delivery systemsfused deposition modellingpowder bed fusionvat photopolymerization

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Pharmaceutical Sciences

Background:

  • Additive manufacturing, or 3D printing, offers transformative potential in medicine and drug delivery.
  • The development of the first US FDA-approved 3D printed tablet has spurred significant research interest.
  • 3D printing facilitates a move towards personalized medicine, challenging traditional dosing methods.

Purpose of the Study:

  • To review recent advancements in modified drug delivery systems utilizing additive manufacturing technologies.
  • To highlight the impact of 3D printing on personalized medicine and drug dosing.

Main Methods:

  • Review of current literature on additive manufacturing techniques in drug delivery.
  • Analysis of applications of various 3D printing technologies in creating modified drug delivery systems.

Main Results:

  • Additive manufacturing enables the creation of customized drug delivery systems.
  • 3D printing allows for precise control over drug release profiles.
  • The technology supports the development of complex dosage forms tailored to individual patient needs.

Conclusions:

  • 3D printing represents a significant advancement in drug delivery, paving the way for personalized medicine.
  • Continued innovation in additive manufacturing will further enhance the capabilities of modified drug delivery systems.