Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hormonal Regulation01:33

Hormonal Regulation

33.1K
The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
33.1K
Gonadal and Placental Hormones01:24

Gonadal and Placental Hormones

1.4K
The gonads, namely the testes in males and the ovaries in females, are pivotal in producing gonadal hormones that orchestrate the intricate processes of sexual development and reproduction.
In males, testosterone is the primary gonadal androgen. It plays a central role in the maturation of male reproductive organs — the penis and testes. Additionally, testosterone is instrumental in the development of secondary sexual characteristics — a deep voice as well as facial and pubic hair...
1.4K
Menopause01:28

Menopause

157
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
157
Requirements for Human Life01:26

Requirements for Human Life

8.1K
The Earth and its atmosphere have provided humans with air, water, and food, but these are not the only requirements for survival. Humans also require a specific range of temperature and pressure that the Earth and its atmosphere provides.
Oxygen
Atmospheric air is only about 20 percent oxygen, but that oxygen is a key component of the chemical reactions that keep the body alive, including the reactions that produce ATP. Brain cells are susceptible to a lack of oxygen because they require a...
8.1K
Secretory Phase01:19

Secretory Phase

707
The secretory phase of the menstrual cycle, spanning from day 14 to 28 in a typical 28-day cycle, is a period of significant physiological changes in the female reproductive system. This phase commences immediately after ovulation and is characterized by the preparation of the endometrium for potential embryo implantation.
Following ovulation, the corpus luteum, a temporary endocrine structure, produces progesterone and estrogens. These hormones stimulate the growth and coiling of endometrial...
707
Physiological Barriers01:25

Physiological Barriers

3.5K
Physiological barriers are semi-permeable cellular structures restricting drug diffusion into intracellular compartments and tissues. There are six types of physiological barriers: blood endothelial, cell membrane, blood-brain, blood-cerebrospinal fluid (CSF), blood-placenta, and blood-testis barriers.
The blood endothelial barrier is the most porous of these. It allows all small ionized, un-ionized, and lipophilic molecules to pass through the endothelial lining into the interstitial space...
3.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Direct Growth of Na-Ion Conducting Na<sub>3</sub>O<sub>15</sub>Si<sub>6</sub>Y Solid Glass Electrolyte With Reduced Interfacial Resistance for Safer Room-Temperature Sodium-Sulfur Pouch Cells.

Angewandte Chemie (International ed. in English)·2026
Same author

Innovations in Corneal Transplantation: The Role of Eye Banks, Donor Corneas, and Artificial Alternatives in Combating Worldwide Corneal Blindness.

Romanian journal of ophthalmology·2026
Same author

Scabies as a Neglected Tropical Disease: A Comprehensive Review of Pathogenesis, Epidemiology, Clinical Manifestations, Diagnosis and Treatment.

The Yale journal of biology and medicine·2026
Same author

An aluminum-doped sodium manganese hexacyano ferrate cathode for high-rate safe Na-ion batteries.

Chemical communications (Cambridge, England)·2025
Same author

Combined thoracic segmental spinal anesthesia and erector spinae plane block in high-risk patients undergoing thoracoscopic surgery: A case series.

Saudi journal of anaesthesia·2025
Same author

A Comparative Analysis of Magnesium Sulfate Administered Intravenously Versus Perineurally as an Additive to Ropivacaine in Supraclavicular Brachial Plexus Block Under Ultrasound Guidance: A Randomized Clinical Trial.

Cureus·2024

Related Experiment Video

Updated: Jun 29, 2025

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
06:55

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus

Published on: December 5, 2015

13.4K

Natural Physiological Changes During Pregnancy.

Mahesh Chandra1, Ansar Ahmad Paray1

  • 1Centre for Interdisciplinary Biomedical Research, Adesh University, Bathinda, India.

The Yale Journal of Biology and Medicine
|April 1, 2024
PubMed
Summary

Pregnancy induces significant physiological and biochemical changes to support fetal development and prepare for childbirth. Differentiating these normal adaptations from disease symptoms is crucial for accurate maternal healthcare.

Keywords:
Adrenal gland changesAnatomical ChangesCardiac changesGlucose metabolismLipid metabolism changesPituitary gland changesProtein metabolismRespiratory changesThyroid hormone changeshematological changes

More Related Videos

Analysis of Electrocardiograms and Behavior in Mice from Pregnancy to Lactation Period
06:40

Analysis of Electrocardiograms and Behavior in Mice from Pregnancy to Lactation Period

Published on: April 5, 2024

429
Author Spotlight: Enhancing the Offspring Health in Rats with Maternal Exercise During Pregnancy
05:17

Author Spotlight: Enhancing the Offspring Health in Rats with Maternal Exercise During Pregnancy

Published on: April 5, 2024

751

Related Experiment Videos

Last Updated: Jun 29, 2025

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
06:55

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus

Published on: December 5, 2015

13.4K
Analysis of Electrocardiograms and Behavior in Mice from Pregnancy to Lactation Period
06:40

Analysis of Electrocardiograms and Behavior in Mice from Pregnancy to Lactation Period

Published on: April 5, 2024

429
Author Spotlight: Enhancing the Offspring Health in Rats with Maternal Exercise During Pregnancy
05:17

Author Spotlight: Enhancing the Offspring Health in Rats with Maternal Exercise During Pregnancy

Published on: April 5, 2024

751

Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Physiological Adaptations in Pregnancy

Background:

  • Pregnancy involves profound physiological alterations to accommodate fetal growth and parturition.
  • Biochemical markers can change during gestation, sometimes mimicking pathological conditions.
  • Distinguishing normal pregnancy changes from disease is essential for appropriate clinical management.

Purpose of the Study:

  • To review the key physiological and biochemical modifications during a typical human pregnancy.
  • To provide a guide for differentiating normal gestational changes from signs of illness.
  • To enhance understanding of the adaptive processes in maternal physiology.

Main Methods:

  • Literature review of peer-reviewed articles on pregnancy physiology.
  • Synthesis of data on biochemical and physiological changes throughout gestation.
  • Comparative analysis of normal versus pathological findings in pregnant individuals.

Main Results:

  • Significant alterations in cardiovascular, respiratory, and metabolic systems are observed.
  • Hormonal shifts lead to predictable changes in various biochemical analytes.
  • Understanding these normative ranges aids in the interpretation of clinical findings.

Conclusions:

  • Pregnancy is a state of dynamic physiological adaptation.
  • Recognizing typical gestational changes is fundamental for accurate diagnosis and care.
  • This review highlights critical physiological shifts essential for obstetric practice.