Related Experiment Video

Updated: Jun 29, 2025

Assessment of Glutamine as a Fuel Source for Alveolar Macrophages Exposed to Chronic Ethanol Using an Extracellular Flux Bioanalyzer
08:37

Assessment of Glutamine as a Fuel Source for Alveolar Macrophages Exposed to Chronic Ethanol Using an Extracellular Flux Bioanalyzer

Published on: November 15, 2024

320

Pneumocystis Pneumonia in a Patient With Alcoholic Hepatitis

Emily Krier1, Ursulina Tomczak1, Thomas Checketts2

  • 1Creighton University School of Medicine, Omaha, NE.

ACG Case Reports Journal
|April 1, 2024
PubMed

Insights

Pneumocystis jirovecii pneumonia (PJP) is rare in patients with alcoholic hepatitis and cirrhosis. Early recognition of alcohol-related liver damage as a risk factor is crucial for managing this severe lung infection.

Area of Science:

  • Medical Mycology
  • Hepatology
  • Pulmonology

Background:

  • Pneumocystis jirovecii pneumonia (PJP) commonly affects immunocompromised individuals.
  • Alcoholic hepatitis and cirrhosis are significant risk factors for opportunistic infections.
  • Literature on PJP in patients with alcoholic liver disease is sparse.

Observation:

  • A case of PJP was diagnosed in a patient with alcoholic hepatitis and underlying cirrhosis.
  • The patient presented with pulmonary symptoms indicative of PJP.

Findings:

  • PJP in the context of alcoholic hepatitis and cirrhosis is associated with a poor prognosis.
  • This specific patient demographic exhibits a high mortality rate.
  • Alcohol use leading to liver damage is identified as a critical etiological factor for PJP.

Implications:

  • Clinicians should consider PJP in patients with a history of alcohol use and liver damage.
  • Prompt diagnosis and management of PJP are essential in this vulnerable population.
  • Increased awareness of this association may improve patient outcomes and reduce mortality.
Keywords:
Pneumocystis jirovecii pneumoniaalcohol induced liver injuryalcohol use disorder

More Related Videos

Histological Analyses of Acute Alcoholic Liver Injury in Zebrafish10:45

Histological Analyses of Acute Alcoholic Liver Injury in Zebrafish

Published on: May 25, 2017

14.3K
Visualization and Analysis of Blood Flow and Oxygen Consumption in Hepatic Microcirculation: Application to an Acute Hepatitis Model10:40

Visualization and Analysis of Blood Flow and Oxygen Consumption in Hepatic Microcirculation: Application to an Acute Hepatitis Model

Published on: August 4, 2012

12.7K

Related Concept Videos

Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
233
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
262
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
242
Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
206
Pneumonia IV: Management01:28

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
324
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
87