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Clinico-Demographic Parameters of Oral Fungal Infections: An Institutional Retrospective Study
Kamala S Devi1, Abilasha R2, Suvarna Kizhakkoottu2
1Dentistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.
Abstract:
Introduction Most fungal infections are responsive to antifungal therapy. However, failure to diagnose the same can significantly affect the quality of lives of patients. Timely identification of fungal infections and their association with varied demographic and clinical parameters will help in improving the prognosis of the patient. The present study aims to evaluate the prevalence of fungal infections among various age groups and genders and also to evaluate the association of fungal infections with demographic parameters. Methods This study included a sample size of n = 600. The demographic and clinical details were compiled and transferred to IBM SPSS Version 23 software (IBM Corp., Armonk, NY) for statistical analysis. Descriptive and Pearson chi-square tests were used to analyze the association of the type of fungal infection with gender, age, and comorbidities. A p-value of less than 0.05 is considered statistically significant. Results Angular cheilitis (40%, 240), followed by denture stomatitis (37.5%, 225), were the most common type of fungal infection among the sample population, and the elderly age group (51-72 years) was the most affected. Angular cheilitis was the most common infection among both males (21.4%, 128) and females (18.6%, 112), but candidiasis was reported more in females (18%, 108) than males (3%, 18) (p = 0.00). Angular cheilitis (32%, 192) and candidiasis (18%, 108) were more observed in association with anemia; however, denture stomatitis (34%, 204) was significantly higher among diabetics (p = 0.00). Conclusion The identification of associated systemic and demographic factors is as important as the treatment of fungal infection itself. The recognition of fungal infections and the role of parameters like age, gender, and systemic comorbidities in the development of fungal infections will have valuable implications for public health. Future research is required for a clear understanding of the same.
Insights
Fungal infections like angular cheilitis and denture stomatitis are common, particularly in the elderly. Associations with gender, anemia, and diabetes highlight the importance of demographic and clinical factors in fungal infection prevalence.
Area of Science:
- Medical Mycology
- Public Health
- Epidemiology
Background:
- Fungal infections significantly impact patient quality of life.
- Timely diagnosis and understanding demographic associations are crucial for improving patient prognosis.
- Prevalence varies across different age groups and genders.
Purpose of the Study:
- To evaluate the prevalence of fungal infections across various age groups and genders.
- To assess the association between fungal infections and demographic parameters.
- To identify clinical factors linked to specific fungal infections.
Main Methods:
- A sample size of 600 participants was analyzed.
- Demographic and clinical data were collected and analyzed using IBM SPSS Version 23.
- Descriptive statistics and Pearson chi-square tests were employed to determine associations (p < 0.05).
Main Results:
- Angular cheilitis (40%) and denture stomatitis (37.5%) were the most prevalent fungal infections.
- The elderly (51-72 years) showed the highest prevalence.
- Candidiasis was more common in females (18%) than males (3%) (p=0.00); denture stomatitis was higher in diabetics (p=0.00).
Conclusions:
- Identifying associated systemic and demographic factors is critical for managing fungal infections.
- Understanding the role of age, gender, and comorbidities in fungal infections has public health implications.
- Further research is needed for a comprehensive understanding of these associations.
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