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Updated: Jun 29, 2025

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
Published on: December 10, 2012
Being Heterogeneous Is Advantageous: Extreme Brownian Non-Gaussian Searches
Vittoria Sposini1, Sankaran Nampoothiri2, Aleksei Chechkin3,4,5
1Faculty of Physics, University of Vienna, Kolingasse 14-16, 1090 Vienna, Austria.
Abstract:
Redundancy in biology may be explained by the need to optimize extreme searching processes, where one or few among many particles are requested to reach the target like in human fertilization. We show that non-Gaussian rare fluctuations in Brownian diffusion dominates such searches, introducing drastic corrections to the known Gaussian behavior. Our demonstration entails different physical systems and pinpoints the relevance of diversity within redundancy to boost fast targeting. We sketch an experimental context to test our results: polydisperse systems.
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