Giant frontal sinus mucocele mimicked a primary brain tumor: A case report

Hamidreza Shojaei1, Reza Mollahoseini2, Saeed Kargar-Soleimanabad3

  • 1Department of Neurosurgery, Imam Khomeini Hospital, Mazandaran University of Medical Sciences, Sari, Mazandaran, Iran.

Abstract

Insights

Tumefactive frontal sinus mucoceles can mimic brain tumors, leading to misdiagnosis. This case highlights the importance of considering mucoceles in the differential diagnosis of intracranial masses presenting with neurological symptoms.

Area of Science:

  • Neurology
  • Neurosurgery
  • Otolaryngology

Background:

  • Frontal sinus mucoceles, though typically causing orbital issues, can rarely lead to intracranial complications.
  • Tumefactive and giant mucoceles present a diagnostic challenge, often resembling intracranial tumors.

Observation:

  • A 24-year-old male presented with a generalized tonic-clonic seizure.
  • Initial imaging demonstrated large bilateral frontal lobe masses.
  • Surgical exploration revealed mucoceles originating from the frontal and paranasal sinuses.

Findings:

  • Frontal sinus mucoceles can manifest as tumefactive lesions.
  • These lesions radiologically and clinically mimic intracranial tumors.
  • Misdiagnosis is common due to varied presentations.

Implications:

  • Highlights the need to include mucoceles in the differential diagnosis for intracranial masses.
  • Emphasizes the importance of comprehensive evaluation for patients with seizures and apparent brain lesions.
  • Underscores the potential for sinus pathology to present with severe neurological manifestations.