Related Experiment Video
Updated: Jun 29, 2025

08:41
Mouse Round Spermatid Injection
Published on: January 26, 2024
722
Semen Cryopreservation in Men with Cancer: Identifying Patterns and Challenges
Braian Ledesma1, Katherine Campbell1, Akhil Muthigi1
1Desai Sethi Urology Institute, University of Miami Miller School of Medicine, Miami, FL.
Summary
Only 52% of male cancer patients completed semen cryopreservation after referral, with older age, financial burden, and lack of interest being barriers. Increased awareness and access to fertility preservation are crucial.
Area of Science:
- Oncology
- Reproductive Urology
- Medical Ethics
Background:
- Fertility preservation is recommended for male cancer patients before chemotherapy.
- Semen cryopreservation is a key fertility preservation option.
Purpose of the Study:
- Determine the rate of semen cryopreservation completion post-referral in male cancer patients.
- Identify factors influencing completion and reasons for non-compliance.
Main Methods:
- Retrospective review of electronic medical records for male cancer patients referred for fertility preservation.
- Analysis of cancer type, cryopreservation rates, and documented reasons for opting out.
Main Results:
- 52% (67/128) of referred male cancer patients underwent semen cryopreservation.
- Patients not completing the procedure tended to be older (median 38 vs. 33 years).
- Primary reasons for non-completion included financial burden and lack of interest.
Conclusions:
- Despite recommendations, only half of eligible male cancer patients complete semen cryopreservation.
- Barriers such as cost and patient interest require further investigation.
- Strategies to improve access and awareness of fertility preservation are needed.
Related Concept Videos
Infertility in Males
261
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
261
Spermatogenesis
102.4K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
102.4K
Disorders of the Male Reproductive System
404
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
404

