Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

208
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
208
Large Intestine01:09

Large Intestine

744
The large intestine is divided into three main regions: the cecum, colon, and rectum. Extending from the ileocecal valve to the anus, it frames the small intestine on three sides.
The ileocecal sphincter, a mucous membrane fold, guards the opening from the ileum to the large intestine. This valve permits material from the small intestine to pass into the large intestine. Attached to the ileocecal valve is the cecum. This small pouch, approximately 6 cm long, has a twisted, coiled tube known as...
744
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

145
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
145
Feces Formation and Defecation01:26

Feces Formation and Defecation

875
After spending 3 to 10 hours in the large intestine, chyme loses a lot of water and becomes feces, the final product of digestion. Feces consist of undigested dietary fiber such as cellulose, mucus, sloughed-off epithelial cells, and microbes. The descending and sigmoid colon stores feces and uses haustral contractions to dry it out but retains enough water to give it a semi-solid texture.
The mass peristalsis then pushes the feces into the rectum, which stretches the rectal walls to activate...
875
Cystic Fibrosis: Pathogenesis01:23

Cystic Fibrosis: Pathogenesis

229
Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
229
Histology of the Large Intestine01:26

Histology of the Large Intestine

745
The large intestine, a vital component of the gastrointestinal tract, is structured with four main layers: the mucosa, submucosa, muscularis, and serosa. Each layer performs a distinct role in facilitating the smooth functioning of the large intestine.
The innermost mucosa layer comprises simple columnar epithelium, lamina propria, and muscularis mucosae. This layer is primarily populated with absorptive cells, tasked with water absorption, and goblet cells, responsible for secreting mucus to...
745

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Criteria for Hidradenitis Suppurativa Competence Centers.

Dermatology and therapy·2026
Same author

Patients' preference regarding patient reported outcome measures (PROMs) for hidradenitis suppurativa, a cross-sectional multi-center study.

Dermatology (Basel, Switzerland)·2026
Same author

Evaluating the diagnostic accuracy of a screening questionnaire for detecting hidradenitis suppurativa: a pooled analysis of accuracy measures from the Global Hidradenitis Suppurativa Atlas (GHiSA) study.

The British journal of dermatology·2026
Same author

The role of surgery in hidradenitis suppurativa: Expert-based holistic approaches.

Clinical and experimental dermatology·2026
Same author

Delphi consensus: First-line use of biologics and small molecules in hidradenitis suppurativa.

Journal of the European Academy of Dermatology and Venereology : JEADV·2026
Same author

Perianal Comedones: A Case Series of Five Patients and a Possible Association With Previously Described Perianal Cysts.

Actas dermo-sifiliograficas·2025
Same journal

Management of Generalized Pustular Psoriasis Flare with Intravenous Spesolimab Followed by Long-Term Treatment with Subcutaneous Spesolimab: A Case Report.

Case reports in dermatology·2026
Same journal

Paraneoplastic Pemphigus Associated with Follicular Lymphoma, Sjögren's Syndrome, and Bronchiolitis Obliterans: A Case of Prolonged Survival.

Case reports in dermatology·2026
Same journal

Tofacitinib in Overlapping Autoimmune and Autoinflammatory Disorders: A Case Report of a Dual Graham-Little-Piccardi-Lasseur Syndrome and Hidradenitis Suppurativa.

Case reports in dermatology·2026
Same journal

Dapsone for Treatment of a Neutrophilic Predominant Variant of Polymorphous Light Eruption: A Case Report.

Case reports in dermatology·2026
Same journal

Cellulitis Caused by Mixed Infection with Group A Streptococci and Non-Toxigenic tox-Gene-Bearing <i>Corynebacterium diphtheriae</i>: A Case Report.

Case reports in dermatology·2026
Same journal

Preconditioning with 1,570-nm Laser before Reduction Mammoplasty in a Patient with a Predisposition for Keloid Scars: A Case Report.

Case reports in dermatology·2026
See all related articles

Related Experiment Video

Updated: Jun 29, 2025

Rectal Organoid Morphology Analysis ROMA: A Diagnostic Assay in Cystic Fibrosis
07:56

Rectal Organoid Morphology Analysis ROMA: A Diagnostic Assay in Cystic Fibrosis

Published on: June 10, 2022

2.8K

The Cystic Sponge Anus.

Hessel H van der Zee1, Pim Aarts1

  • 1Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands.

Case Reports in Dermatology
|April 3, 2024
PubMed
Summary
This summary is machine-generated.

A rare "cystic sponge anus" condition, characterized by a spongy perianal appearance with cysts and comedones, was observed in a patient with hidradenitis suppurativa (HS). Further research is needed to understand its association with HS and other factors.

Keywords:
Anal cystsCase reportHidradenitis suppurativaPerianal pathology

More Related Videos

Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment
04:05

Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment

Published on: May 31, 2024

362
Colon Ascendens Stent Peritonitis CASP - a Standardized Model for Polymicrobial Abdominal Sepsis
06:45

Colon Ascendens Stent Peritonitis CASP - a Standardized Model for Polymicrobial Abdominal Sepsis

Published on: December 18, 2010

19.5K

Related Experiment Videos

Last Updated: Jun 29, 2025

Rectal Organoid Morphology Analysis ROMA: A Diagnostic Assay in Cystic Fibrosis
07:56

Rectal Organoid Morphology Analysis ROMA: A Diagnostic Assay in Cystic Fibrosis

Published on: June 10, 2022

2.8K
Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment
04:05

Author Spotlight: Developing a Rat Model for Pouchitis Research and Treatment

Published on: May 31, 2024

362
Colon Ascendens Stent Peritonitis CASP - a Standardized Model for Polymicrobial Abdominal Sepsis
06:45

Colon Ascendens Stent Peritonitis CASP - a Standardized Model for Polymicrobial Abdominal Sepsis

Published on: December 18, 2010

19.5K

Area of Science:

  • Dermatology
  • Pathology

Background:

  • Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition affecting hair follicles.
  • Surgical management for HS can sometimes lead to unexpected cutaneous findings.

Observation:

  • A unique case of a 62-year-old male patient presented with asymptomatic, spongy perianal skin.
  • The affected area exhibited multiple orifices, cavities, cysts, and giant comedones.
  • Histopathology revealed dilated hair follicles filled with keratin and hair shafts.

Findings:

  • The spongy appearance is hypothesized to result from the spontaneous extrusion of follicular contents.
  • This condition, termed "cystic sponge anus," may be linked to HS, smoking, and male gender.
  • It is potentially another manifestation of an occlusive follicular disease.

Implications:

  • The findings suggest a possible association between "cystic sponge anus" and HS.
  • Further investigation is warranted to determine the prevalence and associated conditions of this entity.
  • Understanding this association could improve diagnostic and therapeutic approaches for related follicular disorders.