Molecular aspects of cervical cancer: a pathogenesis update

Verónica Vallejo-Ruiz1, Lourdes Gutiérrez-Xicotencatl2, Oscar Medina-Contreras3

  • 1Centro de Investigación Biomédica de Oriente, Instituto Mexicano del Seguro Social, Puebla, Mexico.

Frontiers in Oncology
|April 3, 2024
PubMed
Summary

Human papillomavirus (HPV) genome integration correlates with cervical lesion severity. Viral oncoproteins E5, E6, and E7 drive cancer hallmarks, with new insights from next-generation sequencing aiding biomarker discovery.

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