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Association Between Baseline Echocardiographic Parameters and Acute Coronavirus Disease 2019 Infection in
Jin Wang1, Dongmei Yang1, Cheng Cao2
1Department of Echocardiography, The First Affiliated Hospital of University of Science and Technology of China (USTC), Hefei, CHN.
Insights
Baseline echocardiographic parameters, including left ventricular ejection fraction and A-wave velocity, are independent risk factors for new-onset coronavirus disease 2019 (COVID-19) infection in hospitalized patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Medical Imaging
Background:
- The COVID-19 pandemic posed significant challenges to healthcare systems globally.
- Understanding risk factors for COVID-19 infection is crucial for patient management.
- Echocardiography plays a vital role in assessing cardiac function.
Purpose of the Study:
- To investigate the association between baseline clinical and echocardiographic parameters and new-onset COVID-19 infection.
- To identify specific echocardiographic markers predictive of COVID-19 infection in hospitalized patients.
Main Methods:
- Retrospective analysis of 100 hospitalized patients during the COVID-19 outbreak in China.
- Comparison of clinical and echocardiographic data between patients with and without COVID-19 infection.
- Univariate and multivariate analyses to determine independent risk factors.
Main Results:
- Patients with COVID-19 infection were older, more likely male, and had higher rates of heart failure and hypertension.
- Lower left ventricular ejection fraction (LVEF) and higher A-wave velocity were observed in COVID-19 patients.
- Baseline LVEF and A-wave velocity were identified as independent risk factors for COVID-19 infection.
Conclusions:
- Baseline echocardiographic parameters are significantly associated with acute COVID-19 infection.
- Echocardiographic findings can serve as important indicators for COVID-19 risk in hospitalized individuals.
- No significant changes in echocardiographic parameters were noted during follow-up in either group.
Abstract:
Background The current study aimed to examine the association between baseline clinical and echocardiographic parameters with new-onset coronavirus disease 2019 (COVID-19) infection. Methodology We retrospectively enrolled consecutive hospitalized patients from our center during the national outbreak of the COVID-19 pandemic in China. Overall, 100 patients were enrolled, including 38 patients with COVID-19 infection. Results Compared with those without infection, patients with COVID-19 infection were more likely male (63.2% vs. 35.5%, p = 0.008), were older (59.08 vs. 52.35 years, p = 0.022), had higher heart failure (31.6% vs. 11.3%, p = 0.018) and hypertension (52.6% vs. 30.6%, p = 0.036) rates, had lower left ventricular ejection fraction (LVEF) (61.16% vs. 65.76%, p = 0.018), had higher A-wave velocity (86.84 vs. 73.63 cm/s, p = 0.003), and had and lower E/A ratio (0.85 vs 1.04, p = 0.015). On univariate and multivariate analysis, baseline echocardiographic parameters (LVEF and A-wave velocity) were independent risk factors for COVID-19 infection. There were no significant changes in echocardiographic parameters during the one-month follow-up period in patients infected and not infected with COVID-19. Conclusions In conclusion, baseline echocardiographic parameters were significantly associated with acute COVID-19 infection.
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