Optic Nerve Metastasis in Lung Adenocarcinoma
Yelumalai Mangalathevi1,2, Yaakub Azhany1,2, Wan-Hazabbah Wan Hitam1,2
1Department of Ophthalmology and Visual Science, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, Kelantan, MYS.
Cureus
|April 3, 2024
Summary
This case study highlights a rare instance where lung adenocarcinoma metastasized to the optic nerve. Ocular symptoms were the initial presentation, leading to the diagnosis of this advanced lung cancer.
Area of Science:
- Oncology
- Ophthalmology
- Neurology
Background:
- Lung adenocarcinoma can present with rare metastatic patterns.
- Ocular manifestations can be the initial sign of malignancy.
Observation:
- A 59-year-old woman presented with vision loss, headaches, and neurological deficits.
- Imaging revealed an optic nerve metastasis and cerebral infarcts.
- Systemic evaluation confirmed primary lung adenocarcinoma with distant metastasis.
Findings:
- Optic nerve metastasis as the first clinical sign of lung adenocarcinoma.
- Diagnosis facilitated by ocular and neurological symptoms.
- Rapid disease progression and poor prognosis.
Implications:
- Emphasizes the importance of thorough investigation for ocular symptoms.
- Highlights the potential for lung cancer to metastasize to the optic nerve.
- Underscores the need for early detection and comprehensive staging in oncology.
