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The correlation between iodine and metabolism: a review
Le Zhang1, Fangjian Shang2, Cong Liu1
1Department of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, China.
Frontiers in Nutrition
|April 3, 2024
Summary
This review explores the link between iodine intake and metabolic disorders like obesity and diabetes. It examines recent research and underlying mechanisms, as inconsistent findings highlight the need for further understanding of iodine
Area of Science:
- Endocrinology and Metabolism
- Nutritional Science
Background:
- Iodine is essential for thyroid hormone synthesis, crucial for human health.
- Both iodine deficiency and excess pose health risks.
- Extrathyroidal iodine uptake affects various organs independently of thyroid hormones.
Purpose of the Study:
- To review recent research on the relationship between iodine intake and metabolic disorders.
- To explore the mechanisms underlying the association between iodine and metabolic health.
- To address inconsistencies in current study findings.
Main Methods:
- Comprehensive literature review of recent clinical studies.
- Analysis of research investigating iodine's role in metabolic syndrome, obesity, diabetes, hypertension, and dyslipidemia.
- Examination of proposed extrathyroidal mechanisms.
Main Results:
- Clinical studies suggest a connection between iodine intake and various metabolic disorders.
- Existing research presents inconsistent findings regarding the nature and strength of these associations.
- The precise mechanisms linking iodine to metabolic dysregulation remain incompletely understood.
Conclusions:
- Further research is needed to clarify the complex relationship between iodine and metabolic health.
- Understanding the mechanisms is critical for addressing metabolic disorders potentially influenced by iodine status.
- Investigating extrathyroidal effects of iodine may reveal new therapeutic targets.
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