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Updated: Jun 29, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Flashy lungs and sarcoidosis: not always a sign of disease activity
Yousif A Lucinian1, Patrick Martineau2, Francois Harel1
1Institut de Cardiologie de Montréal.
Abstract:
This is the case of a 68-year-old man with known cardiac sarcoidosis undergoing treatment with methotrexate who presented with new onset of dyspnea and lipothymia. FDG-PET/CT revealed pathological uptake within lung parenchyma which resolved following discontinuation of methotrexate, compatible with methotrexate-induced pneumonitis. This is the first case of methotrexate-induced pneumonitis documented by FDG-PET/CT.
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