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The molecular electronic device and the biochip computer: present status.

R C Haddon, A A Lamola

    Proceedings of the National Academy of Sciences of the United States of America
    |April 1, 1985
    PubMed
    Summary
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    Molecular electronic devices (MEDs) and biochip computers (BCCs) promise revolutionary advancements by assembling individual molecules. However, realizing these molecular-scale technologies requires significant scientific breakthroughs and remains a distant goal.

    Area of Science:

    • Nanotechnology and Molecular Electronics
    • Biotechnology and Bioengineering

    Background:

    • The concept of single molecules functioning as electronic devices has long been of interest.
    • The integration of molecular electronic components through biotechnology into biochips or biocomputers is a novel and emerging concept.

    Purpose of the Study:

    • To review approaches for constructing molecular electronic devices (MEDs) and biochip computers (BCCs).
    • To highlight the revolutionary potential and challenges associated with these molecular-scale computing paradigms.

    Main Methods:

    • Discussion of proposed construction techniques for MEDs and BCCs, focusing on bottom-up assembly.
    • Comparison with existing top-down lithographic semiconductor manufacturing processes.

    Main Results:

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    • MEDs/BCCs envision devices built by assembling individual molecular components into arrays.
    • This approach contrasts with current methods, engineering from the molecular level upward.
    • Key challenges include achieving individually accessible functional molecular units and scalable assembly.

    Conclusions:

    • The realization of MEDs and BCCs hinges on fundamental scientific breakthroughs, as the underlying principles are largely unknown.
    • Current biological and fabrication techniques fall short of enabling the utilization and assembly of individual molecules as functional electronic elements.
    • Significant obstacles remain, despite the immense potential of molecular electronics and biochip computing.