Dimension Reduction With Prior Information for Knowledge Discovery
Related Experiment Video
Updated: Jun 29, 2025

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports
Published on: October 13, 2023
Abstract:
This paper addresses the problem of mapping high-dimensional data to a low-dimensional space, in the presence of other known features. This problem is ubiquitous in science and engineering as there are often controllable/measurable features in most applications. To solve this problem, this paper proposes a broad class of methods, which is referred to as conditional multidimensional scaling (MDS). An algorithm for optimizing the objective function of conditional MDS is also developed. The convergence of this algorithm is proven under mild assumptions. Conditional MDS is illustrated with kinship terms, facial expressions, textile fabrics, car-brand perception, and cylinder machining examples. These examples demonstrate the advantages of conditional MDS over conventional dimension reduction in improving the estimation quality of the reduced-dimension space and simplifying visualization and knowledge discovery tasks. Computer codes for this work are available in the open-source cml R package.
Related Concept Videos
Downsampling
The Fourier transform of the decimated sequence reveals a combination of scaled and shifted versions of the original spectrum. This...
Block Diagram Reduction
The first step in this process is the identification and relocation of a branch point. A branch point, where a...
Quantifying and Rejecting Outliers: The Grubbs Test
Statistical Inference Techniques in Hypothesis Testing: Parametric Versus Nonparametric Data
Parametric statistics, as the name suggests, assumes that data follow a specific distribution, often a normal distribution. This assumption enables robust hypothesis testing and estimation. Parametric methods, like the Student's t-test or Goodness-of-fit test, are frequently employed in biostatistics due to their robustness. For instance,...
Predicting Products: Substitution vs. Elimination
The following factors can influence the mechanisms competing against each other:
Factorial Design

