[Tumor-associated markers as organ-specific antigens of human seminal plasma. I. Immunologic studies]

We could demonstrate that some constituents of the human seminal plasma must be regarded as organ-specific substances; these are known as characteristic tumor markers in connection with other subjects. Accordingly, the occurrence of the tumor markers Ca 19-9tm, CEA and Ca 12-5tm in samples of normal human seminal plasma shows that these materials must be defined in this case as organ-characteristic markers. We report on different quantitative distribution of these markers and give evidence that the Ca 19-9 antigen only occurs in persons positive with respect to Lewis' blood group.