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    Area of Science:

    • Biomedical Optics
    • Optical Imaging Technologies
    • Medical Diagnostics

    Background:

    • Polarization-sensitive optical coherence tomography (PS-OCT) is crucial for high-resolution imaging.
    • Conventional methods face limitations in sensitivity and imaging range.
    • Advancements are needed for sensitive birefringence imaging in medical contexts.

    Purpose of the Study:

    • To propose a fiber-based, full-range, depth-encoded swept source PS-OCT (SS-PS-OCT) method.
    • To enhance detection sensitivity and imaging range for PS-OCT.
    • To enable high-sensitivity birefringence imaging for medical diagnosis.

    Main Methods:

    • Implementation of a fiber-based, full-range, depth-encoded SS-PS-OCT system.
    • Utilizing spatial phase modulation in the reference arm for full-range OCT images.
    • Acquiring orthogonal polarized OCT images in the high-sensitivity region.

    Main Results:

    • Achieved a detection sensitivity of 67 dB at an imaging depth of 2 mm.
    • Demonstrated higher detection sensitivity compared to conventional depth-encoded SS-PS-OCT.
    • Successfully acquired full-range, high-sensitivity phase retardation images of biological tissues.

    Conclusions:

    • The proposed fiber-based full-range depth-encoded SS-PS-OCT method significantly improves detection sensitivity.
    • This technique is suitable for medical diagnosis requiring long imaging ranges and high sensitivity.
    • Enables advanced birefringence imaging for various clinical applications.