Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rab Proteins01:14

Rab Proteins

3.9K
Rab proteins constitute the largest family of monomeric GTPases, of which 70 members are present in humans. Rab proteins and their effectors regulate consecutive stages of vesicle transport such as vesicle transport, docking, and fusion to the correct recipient membrane.
Rab proteins switch between a cytosolic, GDP-bound inactive state and a membrane-anchored, GTP-bound active state. By themselves, Rabs show slow rates of GDP/GTP exchange and GTP hydrolysis. Thus, Rab proteins are considered...
3.9K
Rab Cascades01:25

Rab Cascades

2.6K
Rab GTPases act in a regulated cascade during membrane fusion, helping the lipid bilayers mix. The Rab family of proteins are active when bound to GTP, and inactive when bound to GDP. Hence, they act as guanine nucleotide-dependent molecular switches. Rab-GTP recognizes and binds to long or short-range tethering proteins to capture the target vesicle. These tethers coordinate with SNAREs on the vesicle and the target membrane to assemble the trans SNARE complex that locks the mixing bilayers.
2.6K
Radical Reactivity: Overview01:11

Radical Reactivity: Overview

2.1K
Radicals, the highly reactive species, gain stability by undergoing three different reactions. The first reaction involves a radical-radical coupling, in which a radical combines with another radical, forming a spin‐paired molecule. The second reaction is between a radical and a spin‐paired molecule, generating a new radical and a new spin‐paired molecule. The third reaction is radical decomposition in a unimolecular reaction, forming a new radical and a spin‐paired...
2.1K
Radical Reactivity: Intramolecular vs Intermolecular01:33

Radical Reactivity: Intramolecular vs Intermolecular

1.7K
Radical reactions can occur either intermolecularly or intramolecularly. In an intermolecular radical reaction, a nucleophilic radical adds to an electrophilic alkene or vice versa. In such reactions, the radical and generally the alkene, which is also called the radical trap, are two different molecules. Additionally, for such intermolecular reactions to occur, the radical trap must be active, present in an excess concentration, and the radical starting material must have a weak...
1.7K
Kirchoff's Rules: Application01:22

Kirchoff's Rules: Application

1.5K
Kirchhoff's rules quantify the current flowing through a circuit and the voltage variations around the loop in a circuit. Applying Kirchhoff's rules generates a set of linear equations that allow us to find the unknown values in circuits. These may be currents, voltages, or resistances.
When applying Kirchhoff's first rule, the junction rule, label the current in each branch and decide its direction. If the chosen direction is wrong, it will have the correct magnitude, although the...
1.5K
Angular Momentum: Rigid Body01:11

Angular Momentum: Rigid Body

8.7K
The total angular momentum of a rigid body can be calculated using the summation of the angular momentum of all the tiny particles rotating in the same plane. Considering all the tiny particles rotating in the x-y plane, the direction of angular momentum of all such particles and that of the rigid body would be perpendicular to the plane of the rotation along the z-axis.
This calculation can get complicated when tiny particles within the rigid body are not rotating in the same plane but have...
8.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Double-Hybrid, but Not Double-Cost: GPU-Accelerated DHDFT for the COMPAS-3 Data Set of Polybenzenoid Hydrocarbons.

Journal of chemical theory and computation·2026
Same author

W1-S<sub>N</sub>2-BH: A Large-Scale CCSD(T)/CBS Kinetic Database.

The journal of physical chemistry. A·2026
Same author

Computing Exchange Coupling Constants in Transition Metal Complexes with Tensor Product Selected Configuration Interaction.

Journal of chemical theory and computation·2026
Same author

Excitation/Relaxation Analysis of Electronic Transitions Using Difference Density Natural Orbitals.

Journal of chemical theory and computation·2026
Same author

Benchmarking Isomerization Energies for <math><semantics><mrow><msub><mrow><mtext>C</mtext></mrow> <mrow><mn>5</mn></mrow></msub></mrow> <annotation>$$ {\mathrm{C}}_5 $$</annotation></semantics></math> - <math><semantics><mrow><msub><mrow><mtext>C</mtext></mrow> <mrow><mn>7</mn></mrow></msub></mrow> <annotation>$$ {\mathrm{C}}_7 $$</annotation></semantics></math> Hydrocarbons: The ISOC7 Database.

Journal of computational chemistry·2026
Same author

Reply to the "Comment on 'Intramolecular Proton-Coupled Hydride Transfers with Relatively Low Activation Barriers'".

The journal of physical chemistry. A·2025
Same journal

Modeling the Clustering of Fumaric/Maleic Acid with Water and Na<sup>+</sup>, Cl<sup>-</sup> Ions.

The journal of physical chemistry. A·2026
Same journal

Determining Binding Energies of Key Fluorinated Refrigerants 1,1,1,2-Tetrafluoroethane, 2,3,3,3-Tetrafluoropropene, and 3,3,3-Trifluoropropene.

The journal of physical chemistry. A·2026
Same journal

Kinetic and Mechanistic Insights into H-Abstraction and Subsequent Isomerization and Decomposition of Monoglyme and Key Combustion Intermediates.

The journal of physical chemistry. A·2026
Same journal

First-Principles Analysis of Protonation-Induced Electronic Effects in Tetrakis(<i>p</i>-aminophenyl)porphyrin (TAPP).

The journal of physical chemistry. A·2026
Same journal

Exploring the Reactivity of the CH Radical toward Nitrous Oxide in the Context of the Interstellar Medium.

The journal of physical chemistry. A·2026
Same journal

Infrared Photodissociation Spectroscopy of Benzene-V<sup>+</sup>(CO)<sub>n</sub> "Piano Stool" Cations.

The journal of physical chemistry. A·2026
See all related articles

Related Experiment Video

Updated: Jun 29, 2025

CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications
08:32

CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications

Published on: August 9, 2022

3.5K

Tribute to Krishnan Raghavachari

Hrant P Hratchian1, Amir Karton2, Nicholas J Mayhall3

  • 1Department of Chemistry and Biochemistry, University of California, Merced, Merced, California 95340, United States.

The Journal of Physical Chemistry. A
|April 4, 2024
PubMed
Summary

No abstract available in PubMed .

More Related Videos

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface
11:54

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Published on: May 8, 2021

4.4K
CRISPR Guide RNA Cloning for Mammalian Systems
06:48

CRISPR Guide RNA Cloning for Mammalian Systems

Published on: October 2, 2018

70.6K

Related Experiment Videos

Last Updated: Jun 29, 2025

CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications
08:32

CRISPR/Cas9 Gene Editing of Hematopoietic Stem and Progenitor Cells for Gene Therapy Applications

Published on: August 9, 2022

3.5K
Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface
11:54

Real-Time Proxy-Control of Re-Parameterized Peripheral Signals using a Close-Loop Interface

Published on: May 8, 2021

4.4K
CRISPR Guide RNA Cloning for Mammalian Systems
06:48

CRISPR Guide RNA Cloning for Mammalian Systems

Published on: October 2, 2018

70.6K