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The Impact of Medication Synchronization on Proportion of Days Covered within the Pediatric Setting
Brooke E Maletic1, Alex Swick1, Leanne Murray2
1From the Department of Pharmacy, Nationwide Children's Hospital, Columbus, Ohio.
Insights
Medication synchronization significantly improved adherence and reduced pharmacy visits for pediatric patients. This service enhances medication management and patient outcomes in children.
Area of Science:
- Pediatric Pharmacy Practice
- Quality Improvement in Healthcare
- Medication Adherence Research
Background:
- Poor medication adherence in pediatric patients leads to worsened disease, increased mortality, and significant healthcare costs.
- Medication synchronization is a proven strategy to improve adherence in adults, but its pediatric application requires further study.
- This project addresses the need to evaluate medication synchronization within a pediatric setting.
Purpose of the Study:
- To implement and assess a medication synchronization service for pediatric patients.
- To evaluate the impact of medication synchronization on medication adherence rates.
- To measure changes in pharmacy utilization and assess patient and staff satisfaction.
Main Methods:
- A single-center, prospective quality improvement project was conducted at Nationwide Children's Hospital.
- Medication adherence was measured using Proportion of Days Covered (PDC) 90 days pre- and post-implementation.
- Pharmacy trips and patient/staff satisfaction were assessed post-implementation.
Main Results:
- A statistically significant increase in PDC was observed post-implementation (Difference: 3.60, P = 0.001).
- A statistically significant decrease in pharmacy trips was noted (Difference: 2.17, P < 0.001).
- Both patients and pharmacy staff reported satisfaction with the medication synchronization service.
Conclusions:
- Medication synchronization is an effective strategy for improving medication adherence in pediatric populations.
- This service reduces the frequency of pharmacy visits for pediatric patients and their caregivers.
- Implementing medication synchronization can enhance the overall quality of care for children with chronic conditions.
Introduction:
Poor adherence to medication regimens accounts for the substantial worsening of disease, death, and increased healthcare costs of approximately $100 billion annually in the United States. Patients participating in medication synchronization had 3.4 to 6.1 times increased odds of adherence, depending on the drug class. Abundant literature supports medication synchronization within the adult population. This IRB-exempt, prospective quality improvement project is an example of implementing and assessing medication synchronization inclusive of the pediatric setting.
Methods:
This study is a single-center, prospective, quality improvement project for patients seen at Nationwide Children's Hospital (NCH) Complex Care Clinic that also fill prescriptions at NCH Outpatient Pharmacies. The project assessed patient medication adherence using the Proportion of Days Covered and the number of trips to the pharmacy 90 days before and 90 days postimplementation. We also assessed patient and pharmacy staff satisfaction 3 months after project implementation.
Results:
There was a statistically significant increase in the number of days covered for patients 90 days postimplementation compared to 90 days before implementation (Difference: 3.60; 95% confidence interval: 1.87, 5.33; P = 0.001). Additionally, there was a statistically significant decrease in pharmacy trips pre- and postimplementation (Difference: 2.17; 95% confidence interval: 1.26, 3.07; P < 0.001). Overall, pharmacy staff and patients reported satisfaction with the service.
Conclusions:
Implementing a medication synchronization service improved medication adherence and decreased trips to the pharmacy within the pediatric population.
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