The Status and Influencing Factors of COVID-19 Vaccination for 3-7-Year-Old Children Born Prematurely
Related Experiment Video
Updated: Jun 29, 2025

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
Jingyun Shi1, Fangping Zhao1, Wanyin Yang2
1Department of NICU, Gansu Provincial Maternal and Child Care Hospital (Gansu Provincial Central Hospital), Lanzhou City, Gansu, 730050, People's Republic of China.
Insights
Most parents know about COVID-19 vaccines, but concerns about safety persist. Promoting vaccination for premature children via social media, especially to lower education groups, is recommended.
Area of Science:
- Pediatrics
- Vaccinology
- Public Health
Background:
- COVID-19 vaccination is crucial for vulnerable populations, including children born prematurely.
- Understanding parental knowledge, attitudes, and influencing factors is key to improving vaccine uptake in this demographic.
Purpose of the Study:
- To investigate the current status of COVID-19 vaccination among children aged 3-7 years born prematurely.
- To identify factors influencing COVID-19 vaccine acceptance and uptake in this specific pediatric group.
Main Methods:
- A convenience sample of 282 parents of preterm infants (born 2016-2019) at Gansu Maternal and Child Health Hospital completed a questionnaire.
- Data on parental knowledge, vaccine perceptions, and demographic factors were collected and analyzed.
Main Results:
- 96.81% of parents were aware of COVID-19 vaccines, primarily obtaining information via WeChat and TikTok.
- Vaccine acceptance was associated with maternal vaccination status, child's age, referral history, prior disease history, and guardian's education level.
- Key concerns for unvaccinated children included vaccine safety and adverse reactions.
Conclusions:
- A high proportion of premature children received COVID-19 vaccination, yet parental concerns remain.
- Targeted public health campaigns on social media platforms like WeChat and TikTok are recommended, focusing on populations with lower educational attainment.
Objective:
To explore the status and influencing factors of COVID-19 vaccination for 3-7-year-old children born prematurely.
Methods:
A questionnaire was administered to parents of preterm infants born between 1 January 2016 and 31 December 2019 in Gansu Maternal and Child Health Hospital using convenience sampling.
Results:
It was found that 96.81% of 282 parents had known about COVID-19 vaccines and acquired COVID-19- and vaccine-related knowledge primarily through WeChat (104/282, 36.88%) and TikTok (91/282, 32.27%). Most parents of the group whose children were vaccinated with a COVID-19 vaccine believed that this approach was effective in preventing COVID-19 (49.75%), whereas most parents of the group whose children were not vaccinated were worried about the adverse reaction and safety of the vaccine (45.88%). According to the regression analysis, the risk factors of children born prematurely receiving a COVID-19 vaccine were no vaccination against COVID-19 in the mothers (odds ratio [OR]=48.489, 95% CI: 6.524-360.406) and in younger children (OR=12.157, 95% CI: 6.388-23.139). Previous history of referral (OR=0.229, 95% CI: 0.057-0.920), history of diseases (OR=0.130, 95% CI: 0.034-0.503) and high educational level of guardians (OR=0.142, 95% CI: 0.112-0.557) were protective factors for children born prematurely to receive COVID-19 vaccination.
Conclusion:
There is a relatively high proportion of children born prematurely receiving COVID-19 vaccination, but some people still have concerns. Publicity in the later stage can be conducted through WeChat, TikTok and other social media platforms, with special attention paid to the populations with lower education levels.
Related Concept Videos
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Vaccinations
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Environmental Influences on Intelligence

