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Three new pterosins from Pteris semipinnata

Weiren Lu¹, Huajun Li¹, Lan Cao¹

¹Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi, PR China.

Natural Product Research

|April 4, 2024

Abstract:

Three new pterosins, named as semipterosin A (1), B (2) and C (3), together with 11 known pterosins (4-14), were isolated from the aerial parts of Pteris semipinnata. Their structures were elucidated by HRESI-MS, NMR spectral data, CD and literature comparisons. Three new pterosins were assessed for their anti-inflammatory activity. Compounds 1-3 inhibited the NF-kB induction by 40.7%, 61.9% and 34.0%, respectively. This is the first report of the isolation of compounds 6-14 from this plant.

Keywords:

Pteridaceae Pteris semipinnata anti-inflammatory pterosin

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