Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer01:03

Rous Sarcoma Virus (RSV) and Cancer

5.1K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...
5.1K
Maxam-Gilbert Sequencing01:05

Maxam-Gilbert Sequencing

11.2K
In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
Challenges of the Maxam-Gilbert Method
The...
11.2K
GPCR Desensitization01:12

GPCR Desensitization

6.0K
G protein-coupled receptor (GPCR) signaling plays a crucial role in cell functioning. GPCR desensitization is an equally essential process. It allows cells to respond to changing environments and regain sensitivity to new stimuli while preventing unnecessary stimulation when no longer needed. Prolonged exposure to stimuli leads to GPCR desensitization. It involves blocking the receptors from binding and activating additional G proteins. This inhibits activation of downstream effectors, thereby...
6.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of two types of numerical problems on the emotions experienced in adults and in 9-year-old children.

PloS one·2023
Same author

Characterization of Multisubstituted Corticotropin Releasing Factor (CRF) Peptide Antagonists (Astressins).

Journal of medicinal chemistry·2016
Same author

Role of hypothalamic corticotropin-releasing factor in mediating alcohol-induced activation of the rat hypothalamic-pituitary-adrenal axis.

Frontiers in neuroendocrinology·2013
Same author

Corticosteroid-dependent plasticity mediates compulsive alcohol drinking in rats.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2012
Same author

Wylie Vale: neuroendocrine master.

Proceedings of the National Academy of Sciences of the United States of America·2012
Same author

CRF receptor antagonist astressin-B reverses and prevents alopecia in CRF over-expressing mice.

PloS one·2011

Related Experiment Video

Updated: Jun 29, 2025

Quantitative Immunofluorescence to Measure Global Localized Translation
09:13

Quantitative Immunofluorescence to Measure Global Localized Translation

Published on: August 22, 2017

9.9K

Roger Guillemin (1924-2024).

Catherine Rivier1

  • 1Salk Institute, La Jolla, CA, USA.

Science (New York, N.Y.)
|April 4, 2024
PubMed
Summary
This summary is machine-generated.

This study honors the foundational contributions of the father of neuroendocrinology. His pioneering work established the field, linking the nervous and endocrine systems.

More Related Videos

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors
16:16

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors

Published on: September 13, 2013

15.2K
A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)
07:01

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

Published on: February 7, 2025

390

Related Experiment Videos

Last Updated: Jun 29, 2025

Quantitative Immunofluorescence to Measure Global Localized Translation
09:13

Quantitative Immunofluorescence to Measure Global Localized Translation

Published on: August 22, 2017

9.9K
Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors
16:16

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors

Published on: September 13, 2013

15.2K
A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)
07:01

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

Published on: February 7, 2025

390

Area of Science:

  • Neuroendocrinology
  • Endocrinology
  • Neuroscience

Background:

  • The field of neuroendocrinology integrates neuroscience and endocrinology.
  • Understanding the interplay between the nervous and endocrine systems is crucial for physiological regulation.

Purpose of the Study:

  • To recognize and highlight the seminal contributions of the "father of neuroendocrinology."
  • To underscore the historical significance of early research in this interdisciplinary field.

Main Methods:

  • Historical review of foundational research.
  • Biographical analysis of key figures in neuroendocrinology.

Main Results:

  • Established the conceptual framework for neuroendocrinology.
  • Pioneered research into hormone-brain interactions.

Conclusions:

  • The work of the "father of neuroendocrinology" laid the groundwork for modern research.
  • His discoveries continue to influence our understanding of human health and disease.