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Related Concept Videos

Acute Pharyngitis01:30

Acute Pharyngitis

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Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
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Chronic Pharyngitis01:23

Chronic Pharyngitis

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Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
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Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

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Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
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COPD: Pathogenesis and Clinical Features01:20

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Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
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Chemotherapy-Induced Nausea and Vomiting: Cannabinoids01:21

Chemotherapy-Induced Nausea and Vomiting: Cannabinoids

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Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
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Updated: Jun 29, 2025

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Headache Associated with Coronavirus Disease 2019.

Pedro Augusto Sampaio Rocha-Filho1

  • 1Division of Neuropsychiatry, Centro de Ciências Médicas, Universidade Federal de Pernambuco (UFPE), Recife, Brazil; Headache Clinic, Hospital Universitario Oswaldo Cruz, Universidade de Pernambuco, Recife, Brazil.

Neurologic Clinics
|April 4, 2024
PubMed
Summary

Headache is common in acute COVID-19 and can persist in 10-20% of patients. Persistent post-COVID headaches may arise from complications, but treatment options are not yet clinically assessed.

Keywords:
COVID-19Disease managementHeadacheHeadache disordersNew daily persistent headachePhysiopathologyPost-acute COVID-19 syndromeSecondary

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Area of Science:

  • Neurology
  • Infectious Diseases
  • Public Health

Background:

  • Headache is a frequent symptom during the acute phase of COVID-19, often presenting early with insidious onset, bilateral location, and moderate to severe intensity.
  • COVID-19 can lead to serious complications like cerebrovascular diseases, rhinosinusitis, meningitis, and intracranial hypertension, which may cause acute and persistent headaches.
  • A significant minority of patients (10-20%) experience headaches that continue beyond the acute infection phase, although headache generally resolves over time.

Purpose of the Study:

  • To summarize the current understanding of headache in COVID-19 patients.
  • To highlight potential causes of persistent headaches post-COVID-19.
  • To note the lack of clinical trials on treating persistent post-COVID-19 headaches.

Main Methods:

  • This abstract is based on a review of existing literature and clinical observations regarding COVID-19 and headache.
  • No specific clinical trials were conducted for this summary.

Main Results:

  • Headache affects approximately 50% of patients in the acute phase of COVID-19.
  • Persistent headaches occur in 10-20% of COVID-19 survivors.
  • Potential causes for persistent headaches include cerebrovascular diseases, rhinosinusitis, meningitis, and intracranial hypertension.

Conclusions:

  • Headache is a prevalent symptom of COVID-19, with a notable percentage experiencing persistent symptoms.
  • While headache generally improves, complications of COVID-19 can lead to prolonged or severe headaches.
  • There is a current lack of evidence-based clinical trials to guide the treatment of persistent post-COVID-19 headaches.