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Area of Science:

  • Ecology
  • Virology
  • Conservation Biology

Background:

  • Anthropogenic disturbances are causing biodiversity loss, altering species composition and potentially disease dynamics.
  • Bat species exhibit varying competence in hosting and transmitting pathogens like coronaviruses (CoVs).
  • Changes in host assemblages can significantly influence the prevalence and spread of infectious diseases.

Purpose of the Study:

  • To investigate the impact of longitudinal changes in bat species assemblages on coronavirus disease dynamics.
  • To identify specific CoV types and their host-specific infection patterns in Ghanaian cave bats.
  • To determine the relationship between bat community diversity, species competence, and CoV prevalence.

Main Methods:

  • Longitudinal sampling of over 2300 cave-dwelling bats across five locations in Ghana over two years.
  • Species identification and assessment of bat assemblage composition.
  • Detection and characterization of coronaviruses (CoVs) in bat populations.
  • Statistical analysis to evaluate the influence of species abundance, community diversity, and bat age on CoV prevalence.

Main Results:

  • Uneven CoV infection patterns were observed, with alpha-CoV 229E-like and SARS-related beta-CoV 2b identified as multi-host pathogens.
  • Prevalence and infection likelihood of these CoVs were significantly influenced by the abundance of highly competent bat species and the presence of naïve subadults.
  • Bat species demonstrated varying CoV competence, with highly competent species being more prevalent in less diverse communities.
  • Less diverse bat assemblages exhibited increased CoV prevalence.

Conclusions:

  • Bat species' varying competence and community diversity are critical factors in determining coronavirus prevalence.
  • Biodiversity conservation, aligned with the One Health framework, is a proactive strategy to mitigate the risk of zoonotic pathogen spread.
  • Understanding host-pathogen dynamics in wildlife is essential for preventing future pandemics.