Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cancer Survival Analysis

Cancer Survival Analysis

Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...

Barrett Esophagus-II: Clinical Manifestations and Management

Barrett Esophagus-II: Clinical Manifestations and Management

Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Interferon-elicited lipoprotein metabolism in lung fibroblasts facilitates premetastatic niche formation.

Nature communications·2026

Same author

Temporal upregulation of TREM2 parallel to M2 macrophage marker expression in tuberculosis: implications for macrophage polarization regulation.

Frontiers in cellular and infection microbiology·2026

Same author

Immunopharmacology of GPR35: Context-driven signaling and functional plasticity in host defense.

Biochemical pharmacology·2026

Same author

A novel ZNF263-SMOX-ROS-TRIB3 signaling axis drives Wnt/β-catenin activation and metastatic progression in colorectal cancer.

Apoptosis : an international journal on programmed cell death·2026

Same author

PDIA6-SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Same author

CA9 targets ITGB1 to accelerate the progression of colorectal cancer by promoting the neutrophil extracellular traps formation.

Journal of translational medicine·2026

Search research articles

Related Experiment Video

Updated: Jun 29, 2025

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment

Published on: December 27, 2024

Surgical options and survival prognosis in geriatric patients beyond average lifespan with locally advanced gastric

Zhen Tian^1,2, Mingyu Xia³, Yifan Cheng^1,2

¹Northern Jiangsu People's Hospital, Clinical Teaching Hospital of Medical School, Nanjing University, Yangzhou, China.

Surgical Endoscopy

|April 4, 2024

Summary

Laparoscopic gastrectomy (LG) shows comparable or better safety than open gastrectomy (OG) for elderly patients with advanced gastric cancer. Experienced surgeons performing LG offer benefits for super-geriatric patients with locally advanced gastric cancer.

Keywords:

Gastric cancer Geriatric Laparoscopic surgery Prognosis

More Related Videos

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma

Published on: August 9, 2016

Related Experiment Videos

Last Updated: Jun 29, 2025

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment

Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment

Published on: December 27, 2024

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma

Published on: August 9, 2016

Area of Science:

Surgical Oncology
Geriatric Medicine
Gastroenterology

Background:

Laparoscopic gastrectomy (LG) appropriateness for super-geriatric patients with locally advanced gastric cancer (LAGC) remains unclear.
Prognostic factors for this patient group require further elucidation.

Purpose of the Study:

To compare surgical and oncological outcomes of LG versus open gastrectomy (OG) in geriatric patients (≥78 years) with LAGC.
To identify prognostic factors influencing long-term survival in this population.

Main Methods:

A monocentric, retrospective, comparative study utilizing 1:1 propensity score matching (PSM).
Primary endpoint: 3-year overall survival. Secondary endpoints: procedure-related variables, postoperative recovery, and complications.
Univariate and multivariate Cox regression analyses were used to identify prognostic factors.

Main Results:

Post-PSM, 61 matched pairs (median age 82 years) were analyzed.
LG group showed lower complication rates (31.1% vs. 49.2%), shorter hospital stay, and less blood loss than OG group.
No significant difference in 3-year overall survival between LG and OG groups. Age-adjusted Charlson Comorbidity Index >6 and TNM stage III were unfavorable prognostic factors.

Conclusions:

Laparoscopic gastrectomy (LG) by experienced surgeons provides comparable or superior safety profiles to open gastrectomy (OG) for super-geriatric patients with LAGC.
LG offers potential benefits in terms of reduced complications and faster recovery for this elderly demographic.