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Xenopus laevis as a Model to Identify Translation Impairment
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Rice OseIF6.1 encodes a eukaryotic translation initiation factor and is essential for the development of grain and

Hongming Guo1,2, Jianqun Lv1,2, Xiangwen Su1,2

  • 1Environment-Friendly Crop Germplasm Innovation and Genetic Improvement Key Laboratory of Sichuan Province, Crop Research Institute, Sichuan Academy of Agricultural Sciences, Chengdu, China.

Frontiers in Plant Science
|April 5, 2024
PubMed

Keywords:
OseIF6.1eukaryotic translation initiation factorgrain shapepollen sterilityseed setting

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Initiation of Translation

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Initiation is the first step of transcription in eukaryotes. Prokaryotic RNA Polymerase (RNAP) can bind to the template DNA and start transcribing. On the other hand, transcription in eukaryotes requires additional proteins, called transcription factors, to first bind to the promoter region in the DNA template. This binding helps recruit the specific RNAP that can assemble on the DNA and start transcription.
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Riboswitches are non-coding mRNA domains that regulate the transcription and translation of downstream genes without the help of proteins. Riboswitches bind directly to a metabolite and can form unique stem-loop or hairpin structures in response to the amount of the metabolite present. They have two distinct regions – a metabolite-binding aptamer and an expression platform.
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