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Anti-inflammatory benefits of semaglutide: State of the art
Habib Yaribeygi1, Mina Maleki2, Tannaz Jamialahmadi3,4
1Research Center of Physiology, Semnan University of Medical Sciences, Semnan, Iran.
Abstract:
Individuals with diabetes often have chronic inflammation and high levels of inflammatory cytokines, leading to insulin resistance and complications. Anti-inflammatory agents are proposed to prevent these issues, including using antidiabetic medications with anti-inflammatory properties like semaglutide, a GLP-1 analogue. Semaglutide not only lowers glucose but also shows potential anti-inflammatory effects. Studies suggest it can modulate inflammatory responses and benefit those with diabetes. However, the exact mechanisms of its anti-inflammatory effects are not fully understood. This review aims to discuss the latest findings on semaglutide's anti-inflammatory effects and the potential pathways involved.
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