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Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
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Bipolar disorder and the gut microbiota: a bibliometric analysis
Xiaoxiao Lin1, Jinyu Huang1, Shuai Wang1
1Hangzhou First People's Hospital, Hangzhou, China.
Frontiers in Neuroscience
|April 5, 2024
Summary
This bibliometric analysis reveals research trends on bipolar disorder and gut microbiota. Key areas include microbiome characteristics, treatment roles, and gut-brain axis connections, highlighting the need for more studies.
Area of Science:
- Psychiatry and Microbiology
- Gut Microbiome Research
- Bibliometric Analysis
Background:
- The relationship between bipolar disorder and gut microbiota is increasingly recognized.
- No comprehensive bibliometric analysis has previously summarized this research field.
- This study aims to analyze the current status and future directions of publications on bipolar disorder and gut microbiota.
Approach:
- A bibliometric analysis was conducted using publications from the Web of Science Core Collection (WoSCC).
- Data analysis was performed using WoSCC's literature analysis tool and VOSviewer 1.6.16.
- 177 publications from 39 countries/regions were identified and analyzed.
Key Points:
- China leads in publications, with Zhejiang University and author Shaohua Hu being highly productive.
- Key research themes include gut microbiome characteristics, treatment implications, gut-brain axis, and microbiota-based interventions.
- High-impact research highlights the association between gut microbiome composition and bipolar disorder severity.
Conclusions:
- This is the first bibliometric study on bipolar disorder and gut microbiota, mapping the research landscape.
- Current research focuses on microbiome diversity, treatment, gut-brain axis, and interventions.
- The field is nascent, necessitating further research to deepen understanding of the gut microbiota-bipolar disorder association.
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