Related Experiment Video
Updated: Jun 29, 2025

Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
Published on: January 16, 2019
Formative Evaluation of CLABSI Adoption and Sustainment Interventions in a Pediatric Intensive Care Unit
Lindsey J Patton1, Angelica Morris1, Amanda Nash1
1From the Children's Critical Care Services and Nursing Research, Dallas, Tex.
Insights
Implementing central line-associated bloodstream infection (CLABSI) bundles in pediatric intensive care units (PICUs) is crucial for patient safety. A champion role significantly aids in the adoption and sustained use of these infection prevention bundles.
Area of Science:
- Implementation Science
- Pediatric Critical Care
- Infection Prevention
Background:
- Central venous catheters are vital in PICUs but increase infection risk.
- Central line-associated bloodstream infections (CLABSI) are severe complications.
- Consistent CLABSI bundle implementation is challenging.
Purpose of the Study:
- To explore CLABSI bundle implementation strategies in a PICU.
- To identify facilitators and barriers to bundle adoption and sustainment.
- To inform quality improvement efforts for evidence-based practices.
Main Methods:
- Mixed-methods formative evaluation.
- Utilized The Consolidated Framework for Implementation Research (CFIR).
- Developed interview guides and data analysis plans based on CFIR.
Main Results:
- Facilitators and barriers were identified across four CFIR domains.
- The 'champion' role emerged as a key strategy for CLABSI bundle adoption.
- This role facilitated both initial adoption and long-term sustainment of the bundle.
Conclusions:
- Implementation Science Frameworks like CFIR are valuable for quality improvement.
- A dedicated champion role is an effective strategy for CLABSI bundle implementation in critical care.
- This approach can improve patient safety by reducing bloodstream infections.
Background:
Pediatric patients require central venous catheters to maintain adequate hydration, nutritional status, and delivery of life-saving medications in the pediatric intensive care unit. Although central venous catheters provide critical medical therapies, their use increases the risk of severe infection, morbidity, and mortality. Adopting an evidence-based central line-associated bloodstream infection (CLABSI) bundle to guide nursing practice can decrease and sustain low CLABSI rates, but reliable and consistent implementation is challenging. This study aimed to conduct a mixed-methods formative evaluation to explore CLABSI bundle implementation strategies in a PICU.
Methods:
The team used The Consolidated Framework for Implementation Research to develop the interview guide and data analysis plan.
Results:
Facilitators and barriers for the CLABSI bundle occurred in four domains: inner setting, process, characteristics of individuals, and innovation characteristics in each cycle that led to recommended implementation strategy opportunities. The champion role was a major implementation strategy that facilitated the adoption and sustainment of the CLABSI bundle.
Conclusions:
Implementation Science Frameworks, such as Consolidated Framework for Implementation Research (CFIR), can be a beneficial framework to guide quality improvement efforts for evidence-based practices such as the CLABSI bundle. Using a champion role in the critical care setting may be an important implementation strategy for CLABSI bundle adoption and sustainment efforts.
Related Concept Videos
Nursing Clinical Information System
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Nursing Interventions II: Selecting and Classifying the Nursing Interventions
Flail Chest-II
Assessment:
1. Clinical Evaluation:
History:
Nursing Evaluation

