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Updated: Jun 29, 2025

Morphological and Functional Evaluation of Ribbon Synapses at Specific Frequency Regions of the Mouse Cochlea
Published on: May 10, 2019
Does Endolymphatic Hydrops Shift the Cochlear Tonotopic Map?
Samantha Stiepan1, Christopher A Shera1, Carolina Abdala1
1Auditory Research Center, Caruso Department of Otolaryngology, University of Southern California, 1640 Marengo St, Los Angeles, CA, United States.
Abstract:
The cochlear tonotopic map determines where along the basilar membrane traveling waves of different frequencies peak. Endolymphatic hydrops has been hypothesized to shift the tonotopic map by altering the stiffness of the cochlear partition, especially in the apex. In this exploratory study performed in a handful of normal and hydropic ears, we report preliminary measurements of interaural differences assayed using behavioral pitch-matching supplemented by measurements of reflection otoacoustic-emission phase-gradient delays.
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