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Updated: Jun 29, 2025

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Data to knowledge in action: A longitudinal analysis of GenBank metadata
Jeff Hemsley1, Jian Qin1, Sarah E Bratt1
1Syracuse University, Syracuse, New York.
Summary
Collaboration in data production, like genetic sequencing, boosts knowledge diffusion, leading to more patents. Larger teams and more connected researchers in data production result in increased patenting activity.
Area of Science:
- Science of science
- Research collaboration networks
- Knowledge diffusion studies
Background:
- Traditional studies focus on publication authorship for collaboration and knowledge diffusion.
- Research collaboration often begins during data production, preceding publication.
- The role of data production networks in knowledge diffusion remains underexplored.
Purpose of the Study:
- To investigate how collaboration in data production networks influences knowledge diffusion.
- To examine the relationship between data production networks and patent generation.
- To highlight the significance of data production in the science of science.
Main Methods:
- Utilized metadata from genetic sequence records in the National Institutes of Health's GenBank database.
- Constructed annual collaboration networks based on data production.
- Employed regression analysis to test hypotheses on network characteristics and patent output.
Main Results:
- Data production team size shows a positive correlation with the number of patents generated annually.
- Increased average connectivity (links) among actors in data production networks is associated with higher patent counts.
- Findings underscore the impact of early-stage research collaboration on downstream knowledge commercialization.
Conclusions:
- Data production collaboration is a significant driver of knowledge diffusion, as evidenced by patent activity.
- The structure and size of data production networks are critical factors influencing innovation.
- This research emphasizes the importance of considering data production in the science of science framework.
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