Human vitreous fibres and vitreoretinal disease

Adult human vitreous structure was studied by dark-field Slit Microscopy in fresh, unfixed preparations of vitreous dissected off the sclera, choroid and retina. Macroscopic fibres oriented in an antero-posterior direction were detected. These fibres inserted at the vitreous base and oriented towards the macula. Significant alterations were observed in this vitreous structure with advanced age. The role of these structures in vitreo-retinal disease is discussed.