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Coronary calcium score in patients with post-surgical hypoparathyroidism

Jhenifer Franco de Souza Sartori1, Maria Luiza Dos Santos1, Aline Stollmeier2

  • 1Universidade Federal do Paraná, Curitiba, PR, Brasil.

Archives of Endocrinology and Metabolism
|April 5, 2024
PubMed

Insights

Patients with post-surgical hypoparathyroidism (HG) did not show increased coronary calcium scores (CACS). Cardiovascular risk calculators indicated higher risk in HG, but CACS was not linked to calcium or vitamin D supplementation.

Area of Science:

  • Cardiology
  • Endocrinology
  • Radiology

Background:

  • Post-surgical hypoparathyroidism is a condition that may affect cardiovascular health.
  • Assessing cardiovascular risk in these patients is crucial for management.

Purpose of the Study:

  • To evaluate the cardiovascular risk in patients with post-surgical hypoparathyroidism.
  • To compare coronary calcium score (CACS) and cardiovascular risk calculators between hypoparathyroid patients and a control group.

Main Methods:

  • A case-control study comparing 29 patients with post-surgical hypoparathyroidism (HG) to 29 matched controls (CG).
  • Thoracic computed tomography was used for CACS evaluation.
  • Cardiovascular risk was calculated using two risk calculators.

Main Results:

  • No significant difference in CACS was observed between HG and CG.
  • Cardiovascular risk calculators indicated a higher risk in the HG group, with no patients in HG classified as low risk.
  • Positive CACS in HG was associated with obesity and high BMI, but not with calcium or vitamin D supplementation.

Conclusions:

  • Patients with post-surgical hypoparathyroidism did not exhibit increased CACS.
  • The observed cardiovascular risk was not directly related to calcium or vitamin D supplementation in this cohort.
Abstract

Keywords:
Hypoparathyroidismcalcium supplementationcardiovascular riskcoronary calcium score

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