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Coronary calcium score in patients with post-surgical hypoparathyroidism
Jhenifer Franco de Souza Sartori1, Maria Luiza Dos Santos1, Aline Stollmeier2
1Universidade Federal do Paraná, Curitiba, PR, Brasil.
Archives of Endocrinology and Metabolism
|April 5, 2024
Summary
Patients with post-surgical hypoparathyroidism (HG) did not show increased coronary calcium scores (CACS). Cardiovascular risk calculators indicated higher risk in HG, but CACS was not linked to calcium or vitamin D supplementation.
Area of Science:
- Cardiology
- Endocrinology
- Radiology
Background:
- Post-surgical hypoparathyroidism is a condition that may affect cardiovascular health.
- Assessing cardiovascular risk in these patients is crucial for management.
Purpose of the Study:
- To evaluate the cardiovascular risk in patients with post-surgical hypoparathyroidism.
- To compare coronary calcium score (CACS) and cardiovascular risk calculators between hypoparathyroid patients and a control group.
Main Methods:
- A case-control study comparing 29 patients with post-surgical hypoparathyroidism (HG) to 29 matched controls (CG).
- Thoracic computed tomography was used for CACS evaluation.
- Cardiovascular risk was calculated using two risk calculators.
Main Results:
- No significant difference in CACS was observed between HG and CG.
- Cardiovascular risk calculators indicated a higher risk in the HG group, with no patients in HG classified as low risk.
- Positive CACS in HG was associated with obesity and high BMI, but not with calcium or vitamin D supplementation.
Conclusions:
- Patients with post-surgical hypoparathyroidism did not exhibit increased CACS.
- The observed cardiovascular risk was not directly related to calcium or vitamin D supplementation in this cohort.
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